Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STIM1 | Q13586 | 6/20 | 0.62 |
| ▸ | ORAI1 | Q96D31 | 6/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.54 |
| ▸ | OGT | O15294 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA5A | P35218 | 2/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.47 |
| ▸ | OXTR | P30559 | 1/20 | 0.47 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29946130 | 0.88 | STIM1 (0.56) | STIM1ORAI1PTGS2PTGS1OGT | |
| SCHEMBL26628288 | 0.88 | STIM1 (0.56) | STIM1ORAI1PTGS2PTGS1OGT | |
| SCHEMBL28864475 | 0.86 | STIM1 (0.54) | STIM1ORAI1PTGS2PTGS1OGT | |
| SCHEMBL26628317 | 0.86 | STIM1 (0.85) | STIM1ORAI1OGTCA1CA2 | |
| SCHEMBL29946211 | 0.86 | STIM1 (0.85) | STIM1ORAI1OGTCA1CA2 | |
| SCHEMBL26628314 | 0.82 | PTGS2 (0.67) | STIM1ORAI1PTGS2PTGS1OGT | |
| SCHEMBL18023900 | 0.82 | PTGS2 (0.58) | STIM1ORAI1PTGS2PTGS1OGT | |
| SCHEMBL29946183 | 0.81 | STIM1 (0.85) | STIM1ORAI1 | |
| SCHEMBL26628283 | 0.81 | STIM1 (0.85) | STIM1ORAI1 | |
| SCHEMBL2190307 | 0.81 | PTGS2 (0.67) | STIM1ORAI1PTGS2PTGS1OGT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115243765-A | Biphenyl compounds as SOCE modulators, compositions and uses thereof | 皮埃蒙特阿米阿伏伽德罗东方大学 | 2022-10-25 | — | — | CN | claimed |
| CN-115243765-A | Biphenyl compounds as SOCE modulators, compositions and uses thereof | 皮埃蒙特阿米阿伏伽德罗东方大学 | 2022-10-25 | — | — | CN | disclosed |