Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6396771 | 1.00 | THRB (0.35) | THRBMEN1KMT2AEPHX1NOS3 | |
| SCHEMBL22061195 | 0.97 | EPHX1 (0.37) | THRBMEN1KMT2AEPHX1ACHE | |
| SCHEMBL18468643 | 0.97 | EPHX1 (0.37) | THRBMEN1KMT2AEPHX1ACHE | |
| SCHEMBL24043588 | 0.97 | EPHX1 (0.37) | THRBMEN1KMT2AEPHX1ACHE | |
| SCHEMBL13716605 | 0.97 | EPHX1 (0.37) | THRBMEN1KMT2AEPHX1ACHE | |
| SCHEMBL23468899 | 0.97 | EPHX1 (0.37) | THRBMEN1KMT2AEPHX1ACHE | |
| SCHEMBL23222175 | 0.94 | — | — | |
| SCHEMBL22680724 | 0.94 | — | — | |
| SCHEMBL23347485 | 0.94 | CYP2C9 (0.30) | NOS3NOS1NOS2 | |
| Cyclohexylamine SCHEMBL916977 | 0.94 | EPHX1 (0.38) | THRBMEN1KMT2AEPHX1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163401-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. (US) | 2020-08-13 | — | — | WO | disclosed |