Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21220106 | 0.97 | CYP2C9 (0.38) | CYP2C9CYP1A2LMNAALDH1A1MAPT | |
| SCHEMBL5951231 | 0.93 | TLR4 (0.41) | CYP2C9CYP1A2LMNAALDH1A1MAPT | |
| SCHEMBL4544760 | 0.93 | TLR4 (0.41) | CYP2C9CYP1A2LMNAALDH1A1MAPT | |
| SCHEMBL23334078 | 0.91 | CYP1A2 (0.43) | CYP2C9CYP1A2LMNAALDH1A1MAPT | |
| SCHEMBL6410601 | 0.87 | CYP2C9 (0.40) | CYP2C9CYP1A2LMNAALDH1A1MAPT | |
| SCHEMBL129995 | 0.85 | — | — | |
| SCHEMBL5691374 | 0.85 | CYP1A2 (0.48) | CYP2C9CYP1A2LMNAALDH1A1MAPT | |
| SCHEMBL9555982 | 0.84 | CYP1A2 (0.58) | CYP2C9CYP1A2LMNAMAPTMAPK1 | |
| SCHEMBL9555985 | 0.84 | CYP1A2 (0.58) | CYP2C9CYP1A2LMNAMAPTMAPK1 | |
| Acetic Acid SCHEMBL8734367 | 0.83 | TLR4 (0.46) | CYP2C9CYP1A2LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8975247-B2 | Methods and compositions of treating a flaviviridae family viral infection | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNION UNIVERSITY (US) | 2015-03-10 | — | — | US | disclosed |
| US-8945420-B2 | Liquid crystal display and liquid crystalline medium | MERCK PATENT GMBH (DE) | 2015-02-03 | — | — | US | disclosed |
| US-8945420-B2 | Liquid crystal display and liquid crystalline medium | MERCK PATENT GMBH (DE) | 2015-02-03 | — | — | US | disclosed |
| US-8945420-B2 | Liquid crystal display and liquid crystalline medium | MERCK PATENT GMBH (DE) | 2015-02-03 | — | — | US | disclosed |
| EP-2562162-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2013-02-27 | — | — | EP | disclosed |
| US-20120307177-A1 | LIQUID CRYSTAL DISPLAY AND LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-12-06 | — | — | US | disclosed |
| US-20120307177-A1 | LIQUID CRYSTAL DISPLAY AND LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-12-06 | — | — | US | disclosed |
| US-20120307177-A1 | LIQUID CRYSTAL DISPLAY AND LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-12-06 | — | — | US | disclosed |
| WO-2011098202-A1 | LIQUID CRYSTAL DISPLAY AND LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2011-08-18 | — | — | WO | disclosed |
| WO-2011098202-A1 | LIQUID CRYSTAL DISPLAY AND LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2011-08-18 | — | — | WO | disclosed |
| US-20100015093-A1 | Methods and compositions of treating a flaviviridae family viral infection | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2010-01-21 | — | — | US | disclosed |
| EP-0688752-B1 | Trifluoro-2-(trans-4-substituted cyclohexyl) ethylenes and process for their production | ASAHI GLASS CO LTD (JP) | 1999-01-13 | — | — | EP | disclosed |
| US-5621147-A | LIQUID CRYSTAL INTERMEDIATES | ASAHI GLASS COMPANY LTD. (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0688752-A1 | Trifluoro-2-(trans-4-substituted cyclohexyl) ethylenes and process for their production | ASAHI GLASS COMPANY LTD. (JP) | 1995-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100015093-A1 | Methods and compositions of treating a flaviviridae family viral infection | EIF2AK2, NSUN3, NSUN2 | CYP2C9 4198/4885CYP1A2 3545/4885LMNA 1328/4885 |
| US-20120307177-A1 | LIQUID CRYSTAL DISPLAY AND LIQUID CRYSTALLINE MEDIUM | CUTA, NEFM, FES | CYP2C9 3493/4885CYP1A2 2680/4885LMNA 175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.