Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 2/20 | 0.57 |
| ▸ | MGLL | Q99685 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 2/20 | 0.54 |
| ▸ | FABP3 | P05413 | 5/20 | 0.53 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.52 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.52 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.52 |
| ▸ | PRKCA | P17252 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL4447458 | 0.94 | DGKA (0.57) | DGKAMGLLALDH1A1MAPTTHRB | |
| Sulfuric Acid SCHEMBL325125 | 0.94 | DGKA (0.57) | DGKAMGLLALDH1A1MAPTTHRB | |
| Sulfuric Acid SCHEMBL9769254 | 0.94 | DGKA (0.57) | DGKAMGLLALDH1A1MAPTTHRB | |
| Sulfuric Acid SCHEMBL2231605 | 0.94 | DGKA (0.57) | DGKAMGLLALDH1A1MAPTTHRB | |
| Sulfuric Acid SCHEMBL5701170 | 0.91 | DGKA (0.57) | DGKAMGLLALDH1A1MAPTTHRB | |
| Sulfuric Acid SCHEMBL7644055 | 0.91 | DGKA (0.61) | DGKAMGLLALDH1A1MAPTTHRB | |
| Sulfuric Acid SCHEMBL7644061 | 0.91 | DGKA (0.61) | DGKAMGLLALDH1A1MAPTTHRB | |
| SCHEMBL8982682 | 0.91 | DGKA (0.69) | DGKAMGLLALDH1A1MAPTTHRB | |
| SCHEMBL8982775 | 0.91 | DGKA (0.69) | DGKAMGLLALDH1A1MAPTTHRB | |
| SCHEMBL607892 | 0.91 | DGKA (0.69) | DGKAMGLLALDH1A1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511924-B | Isolation of micrornas from biological fluids | 西格马-奥尔德里奇有限责任公司 | 2023-11-03 | — | — | CN | disclosed |
| EP-4223286-A2 | SPRAY DRIED COMPOSITIONS HAVING DIFFERENT DISSOLUTION PROFILES AND PROCESSES FOR THEIR PREPARATION | SpecGx LLC (US) | 2023-08-09 | — | — | EP | disclosed |
| EP-3154528-B1 | SPRAY DRIED COMPOSITIONS HAVING DIFFERENT DISSOLUTION PROFILES AND PROCESSES FOR THEIR PREPARATION | SpecGx LLC (US) | 2023-04-05 | — | — | EP | disclosed |
| US-11464741-B2 | Spray dried compositions having different dissolution profiles and processes for their preparation | SpecGx LLC (US) | 2022-10-11 | — | — | US | disclosed |
| EP-3702361-B1 | MICRO RNA ISOLATION FROM BIOLOGICAL FLUID | SIGMA ALDRICH CO LLC (US) | 2022-08-31 | — | — | EP | disclosed |
| EP-3702361-A1 | MICRO RNA ISOLATION FROM BIOLOGICAL FLUID | Sigma Aldrich Co. LLC (US) | 2020-09-02 | — | — | EP | disclosed |
| US-10711266-B2 | Micro RNA isolation from a biological sample | SIGMA-ALDRICH CO. LLC (US) | 2020-07-14 | — | — | US | disclosed |
| US-20190144850-A1 | MICRO RNA ISOLATION FROM BIOLOGICAL FLUID | SIGMA-ALDRICH CO. LLC (US) | 2019-05-16 | — | — | US | disclosed |
| US-10131902-B2 | Micro RNA isolation from biological fluid | SIGMA-ALDRICH CO. LLC (US) | 2018-11-20 | — | — | US | disclosed |
| EP-3154528-A1 | SPRAY DRIED COMPOSITIONS HAVING DIFFERENT DISSOLUTION PROFILES AND PROCESSES FOR THEIR PREPARATION | Mallinckrodt LLC (US) | 2017-04-19 | — | — | EP | disclosed |
| US-20150359743-A1 | SPRAY DRIED COMPOSITIONS HAVING DIFFERENT DISSOLUTION PROFILES AND PROCESSES FOR THEIR PREPARATION | SpecGx LLC | 2015-12-17 | — | — | US | disclosed |
| WO-2015094609-A1 | MICRO RNA ISOLATION FROM BIOLOGICAL FLUID | SIGMA-ALDRICH CO. LLC (US) | 2015-06-25 | — | — | WO | disclosed |
| EP-2115131-B1 | STABILIZED COMPOSITIONS OF THERMOSTABLE DNA POLYMERASE AND ANIONIC DETERGENT | SIGMA ALDRICH CO LLC (US) | 2013-07-31 | — | — | EP | disclosed |
| US-8404464-B2 | Methods of using stabilized compositions of thermostable DNA polymerase and anionic detergent | SIGMA-ALDRICH CO., LLC (US) | 2013-03-26 | — | — | US | disclosed |
| US-20110312035-A1 | STABILIZED COMPOSITIONS OF THERMOSTABLE DNA POLYMERASE AND ANIONIC OR ZWITTERIONIC DETERGENT | SIGMA-ALDRICH CO. (US) | 2011-12-22 | — | — | US | disclosed |
| US-7972828-B2 | a mixture of polymerases and anionic or zwitterionic surfactants, used for protecting DNA during genetic replication | SIGMA-ALDRICH CO. (US) | 2011-07-05 | — | — | US | disclosed |
| WO-2010083844-A1 | METHODS AND USES FOR RNA EXTRACT AND STORAGE | QUANTIBACT A/S (DK) | 2010-07-29 | — | — | WO | disclosed |
| EP-2115131-A2 | STABILIZED COMPOSITIONS OF THERMOSTABLE DNA POLYMERASE AND ANIONIC OR ZWITTERIONIC DETERGENT | Sigma-Aldrich Co. (US) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008077017-A2 | STABILIZED COMPOSITIONS OF THERMOSTABLE DNA POLYMERASE AND ANIONIC OR ZWITTERIONIC DETERGENT | SIGMA-ALDRICH CO. (US) | 2008-06-26 | — | — | WO | disclosed |
| US-20080145910-A1 | STABILIZED COMPOSITIONS OF THERMOSTABLE DNA POLYMERASE AND ANIONIC OR ZWITTERIONIC DETERGENT | SIGMA ALDRICH COMPANY (US) | 2008-06-19 | — | — | US | disclosed |