Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 19/20 | 0.68 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.68 |
| ▸ | JAK1 | P23458 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22324403 | 0.87 | TYK2 (0.69) | TYK2PDE4DJAK1 | |
| SCHEMBL22343291 | 0.86 | TYK2 (0.77) | TYK2PDE4D | |
| SCHEMBL22323999 | 0.84 | TYK2 (0.73) | TYK2PDE4D | |
| SCHEMBL22343290 | 0.83 | TYK2 (0.65) | TYK2PDE4DJAK1 | |
| SCHEMBL20679020 | 0.82 | TYK2 (0.83) | TYK2PDE4D | |
| SCHEMBL20678983 | 0.81 | TYK2 (1.00) | TYK2PDE4D | |
| SCHEMBL22343298 | 0.81 | TYK2 (0.64) | TYK2PDE4D | |
| SCHEMBL22343331 | 0.81 | TYK2 (0.66) | TYK2PDE4D | |
| SCHEMBL20688284 | 0.75 | TYK2 (0.87) | TYK2PDE4D | |
| SCHEMBL23327539 | 0.74 | TYK2 (0.59) | TYK2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163778-A1 | TYK2 PSEUDOKINASE LIGANDS | VENTYX BIOSCIENCES, INC. (US) | 2020-08-13 | — | — | WO | disclosed |