Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | NT5E | P21589 | 2/20 | 0.40 |
| ▸ | GNMT | Q14749 | 2/20 | 0.39 |
| ▸ | AHCY | P23526 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22343707 | 1.00 | BCHE (0.46) | BCHENT5EGNMTAHCYADORA1 | |
| SCHEMBL22343537 | 0.91 | BCHE (0.46) | BCHENT5EGNMTAHCYCHKA | |
| SCHEMBL22343667 | 0.90 | BCHE (0.46) | BCHENT5EGNMTAHCY | |
| SCHEMBL22343765 | 0.90 | BCHE (0.42) | BCHENT5EGNMTAHCYADORA1 | |
| SCHEMBL22343674 | 0.89 | BCHE (0.43) | BCHENT5EGNMTAHCY | |
| SCHEMBL22343662 | 0.88 | BCHE (0.48) | BCHENT5EGNMTAHCYADORA1 | |
| SCHEMBL22343664 | 0.85 | BCHE (0.44) | BCHENT5EGNMTAHCY | |
| SCHEMBL22343609 | 0.85 | BCHE (0.44) | BCHENT5EGNMTAHCY | |
| SCHEMBL29702996 | 0.85 | ADORA1 (0.54) | GNMTADORA1TRPM2 | |
| SCHEMBL22343649 | 0.80 | BCHE (0.45) | BCHENT5EAHCYTRPM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163673-A1 | INHIBITORS OF ADENYLATE-FORMING ENZYME MENE | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2020-08-13 | — | — | WO | disclosed |