Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | AHCY | P23526 | 1/20 | 0.41 |
| ▸ | ADH1A | P07327 | 1/20 | 0.41 |
| ▸ | NT5E | P21589 | 3/20 | 0.41 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.40 |
| ▸ | NADK | O95544 | 2/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.40 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22343665 | 0.91 | BCHE (0.47) | BCHEAHCYNT5ETRPM2 | |
| SCHEMBL22343650 | 0.88 | BCHE (0.45) | BCHEAHCYADH1ANT5ETRPM2 | |
| SCHEMBL22343649 | 0.88 | BCHE (0.45) | BCHEAHCYADH1ANT5ETRPM2 | |
| SCHEMBL22343737 | 0.88 | NT5E (0.38) | BCHEADH1ANT5ENADKIMPDH2 | |
| SCHEMBL22343634 | 0.86 | AHCY (0.45) | BCHEAHCYNT5E | |
| SCHEMBL22343635 | 0.85 | BCHE (0.46) | BCHEAHCYNT5E | |
| SCHEMBL22343633 | 0.84 | BCHE (0.46) | BCHEAHCYNT5ETRPM2 | |
| SCHEMBL22343651 | 0.84 | BCHE (0.48) | BCHEAHCYNT5E | |
| SCHEMBL22343663 | 0.82 | BCHE (0.46) | BCHEAHCYNT5ETRPM2 | |
| SCHEMBL22343607 | 0.81 | BCHE (0.46) | BCHEAHCYNT5ETRPM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020163673-A1 | INHIBITORS OF ADENYLATE-FORMING ENZYME MENE | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2020-08-13 | — | — | WO | disclosed |