SCHEMBL22344210

SCHEMBL22344210

Cn1c(-c2c(O)cccc2F)nc2ccccc21

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDGFRB P09619 1/20 0.51
FGFR1 P11362 1/20 0.51
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
KDM4E B2RXH2 10/20 0.47
GAA P10253 7/20 0.47
LMNA P02545 5/20 0.47
PAX8 Q06710 1/20 0.47
ALDH1A1 P00352 9/20 0.47
NPC1 O15118 7/20 0.47
RAB9A P51151 7/20 0.47
TP53 P04637 5/20 0.47
PKM P14618 5/20 0.47
HSD17B10 Q99714 3/20 0.47
ALOX15 P16050 1/20 0.47
SMN1; SMN2 Q16637 9/20 0.46
MAPT P10636 7/20 0.46
HPGD P15428 4/20 0.46
POLB P06746 1/20 0.45
CA1 P00915 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30145300 1.00 PDGFRB (0.51) PDGFRBFGFR1MEN1KMT2AKDM4E
SCHEMBL30145320 0.89 MEN1 (0.54) PDGFRBFGFR1MEN1KMT2AKDM4E
SCHEMBL22344209 0.89 MEN1 (0.54) PDGFRBFGFR1MEN1KMT2AKDM4E
SCHEMBL3714642 0.76 PDE10A (0.56) MEN1KMT2AKDM4EGAALMNA
SCHEMBL230403 0.76 KDM4E (0.57) MEN1KMT2AKDM4EGAALMNA
SCHEMBL26856371 0.76 ALDH1A1 (0.60) PDGFRBFGFR1MEN1KMT2AKDM4E
SCHEMBL15315659 0.76 MEN1 (0.61) PDGFRBFGFR1MEN1KMT2AKDM4E
SCHEMBL1171430 0.75 MEN1 (0.69) MEN1KMT2AKDM4EGAALMNA
SCHEMBL15426496 0.74 KDM4E (0.41) KDM4E
SCHEMBL19100408 0.73 ALDH1A1 (0.56) PDGFRBFGFR1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12116444-B2 Polymeric anion-conducting membrane EVONIK OPERATIONS GMBH (DE) 2024-10-15 US disclosed
CN-111225939-B Polymeric anion conducting membranes 赢创运营有限公司 2022-12-20 CN disclosed
US-20200262959-A1 POLYMERIC ANION-CONDUCTING MEMBRANE EVONIK OPERATIONS GMBH (DE) 2020-08-20 US disclosed
CN-111225939-A Polymeric anion conducting membranes 赢创运营有限公司 2020-06-02 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12116444-B2 Polymeric anion-conducting membrane TIMM9, TIMM44, TIMM13 PDGFRB 4381/4885FGFR1 4378/4885MEN1 1330/4885
US-20200262959-A1 POLYMERIC ANION-CONDUCTING MEMBRANE TIMM9, TIMM44, TIMM13 PDGFRB 4381/4885FGFR1 4378/4885MEN1 1330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.