Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL293294 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2CA14CA12GRIK1GRIK2 | |
| SCHEMBL295878 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2CA14CA12GRIK1GRIK2 | |
| SCHEMBL293293 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2CA14CA12GRIK1GRIK2 | |
| SCHEMBL295880 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2CA14CA12GRIK1GRIK2 | |
| SCHEMBL2234435 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2CA14CA12GRIK1GRIK2 | |
| SCHEMBL8090761 | 0.87 | SMN1; SMN2 (0.44) | SMN1; SMN2CA14CA12MEN1KMT2A | |
| SCHEMBL9978358 | 0.82 | ALDH1A1 (0.34) | GRIK1GRIK2CYP2C9 | |
| SCHEMBL9978359 | 0.82 | ALDH1A1 (0.34) | GRIK1GRIK2CYP2C9 | |
| SCHEMBL9978356 | 0.82 | ALDH1A1 (0.34) | GRIK1GRIK2CYP2C9 | |
| SCHEMBL9978585 | 0.82 | ALDH1A1 (0.34) | GRIK1GRIK2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2171061-B1 | PREPARATION OF AN ESTERASE | DPX HOLDINGS BV (NL) | 2017-09-27 | — | — | EP | disclosed |
| US-9309503-B2 | Preparation of an esterase | DPX HOLDINGS B.V. (NL) | 2016-04-12 | — | — | US | disclosed |
| US-20110177553-A1 | PREPARATION OF AN ESTERASE | DPX HOLDINGS B.V. (NL) | 2011-07-21 | — | — | US | disclosed |
| EP-2171061-A1 | PREPARATION OF AN ESTERASE | DSM IP Assets B.V. (NL) | 2010-04-07 | — | — | EP | disclosed |
| WO-2009004093-A1 | PREPARATION OF AN ESTERASE | DSM IP ASSETS B.V. (NL) | 2009-01-08 | — | — | WO | disclosed |