Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.43 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | POLB | P06746 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1116275 | 0.77 | KDM4E (0.51) | ALDH1A1KDM4EMAPTPOLBHPGD | |
| SCHEMBL1116268 | 0.75 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTPOLBHPGD | |
| SCHEMBL918714 | 0.69 | KDM4E (0.40) | ALDH1A1KDM4EMAPTPOLBHPGD | |
| SCHEMBL6656195 | 0.69 | ALDH1A1 (0.61) | ALDH1A1KDM4EMAPTPOLBHPGD | |
| SCHEMBL19459416 | 0.68 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPTPOLBHPGD | |
| SCHEMBL30526242 | 0.67 | ALDH1A1 (0.44) | ALDH1A1KDM4EMAPTPOLBHPGD | |
| SCHEMBL19487057 | 0.67 | ALDH1A1 (0.44) | ALDH1A1KDM4EMAPTPOLBHPGD | |
| SCHEMBL19459419 | 0.67 | ALDH1A1 (0.44) | ALDH1A1KDM4EMAPTPOLBHPGD | |
| SCHEMBL19459488 | 0.67 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTPOLBHPGD | |
| SCHEMBL2551317 | 0.67 | KDM4E (0.66) | ALDH1A1KDM4EMAPTPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200262784-A1 | TRIFLUOROMETHOXYLATION OF ARENES VIA INTRAMOLECULAR TRIFLUOROMETHOXY GROUP MIGRATION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2020-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200262784-A1 | TRIFLUOROMETHOXYLATION OF ARENES VIA INTRAMOLECULAR TRIFLUOROMETHOXY GROUP MIGRATION | AHR, AFF2, AFF4 | ALDH1A1 778/4885KDM4E 2013/4885MAPT 3670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.