Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | CES1 | P23141 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18837900 | 0.94 | MAPT (0.58) | MAPTL3MBTL1MAPK1CES1MEN1 | |
| SCHEMBL3047151 | 0.90 | MAPT (0.57) | MAPTL3MBTL1MAPK1CES1MEN1 | |
| SCHEMBL27815181 | 0.88 | MAPT (0.67) | MAPTL3MBTL1MAPK1CES1MEN1 | |
| Diphenylether SCHEMBL6868881 | 0.86 | FFAR1 (0.62) | MAPTL3MBTL1MAPK1CES1MEN1 | |
| SCHEMBL11060793 | 0.85 | KDM4E (0.68) | MAPTL3MBTL1MAPK1CES1MEN1 | |
| SCHEMBL9669280 | 0.84 | MEN1 (0.66) | MAPTL3MBTL1MAPK1CES1MEN1 | |
| SCHEMBL28723007 | 0.83 | MEN1 (0.82) | MAPTL3MBTL1MAPK1CES1MEN1 | |
| SCHEMBL11060783 | 0.83 | MEN1 (0.73) | MAPTL3MBTL1MAPK1CES1MEN1 | |
| SCHEMBL6996891 | 0.82 | TDP1 (0.62) | MAPTL3MBTL1MAPK1CES1MEN1 | |
| SCHEMBL11848975 | 0.82 | MAPT (0.60) | MAPTL3MBTL1MAPK1CES1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113372334-A | 2- (4-methionyl) anilino-4-amino-5-trifluoromethylpyrimidine derivatives and application thereof | 贵州医科大学 | 2021-09-10 | — | — | CN | claimed |
| CN-112592318-A | 2- (4-methionyl) anilino-4-aminopyrimidine derivatives and application thereof | 贵州医科大学 | 2021-04-02 | — | — | CN | claimed |
| CN-104710367-A | Method for synthesizing enzalutamide | UNIV CHINA PHARMA | 2015-06-17 | — | — | CN | claimed |
| CN-103304439-A | Preparation method of 4-amino-2-fluoro-methyl benzamide | UNIV CHANGZHOU | 2013-09-18 | — | — | CN | claimed |
| CN-113372334-B | 2- (4-methionyl) anilino-4-amino-5-trifluoromethylpyrimidine derivatives and application thereof | 贵州医科大学 | 2022-05-03 | — | — | CN | disclosed |
| CN-112592318-B | 2- (4-methionyl) anilino-4-aminopyrimidine derivatives and application thereof | 贵州医科大学 | 2022-05-03 | — | — | CN | disclosed |
| CN-112299938-B | Method for preparing amine compound by reducing amide compound | 中国科学院兰州化学物理研究所 | 2021-12-28 | — | — | CN | disclosed |
| CN-110903286-B | 4, 6-disubstituted pyridine [3,2-d ] pyrimidine compound and preparation and application thereof | 沈阳药科大学 | 2021-09-24 | — | — | CN | disclosed |
| CN-113372334-A | 2- (4-methionyl) anilino-4-amino-5-trifluoromethylpyrimidine derivatives and application thereof | 贵州医科大学 | 2021-09-10 | — | — | CN | disclosed |
| CN-112592318-A | 2- (4-methionyl) anilino-4-aminopyrimidine derivatives and application thereof | 贵州医科大学 | 2021-04-02 | — | — | CN | disclosed |
| CN-110950781-A | Novel diamine, polyamic acid, and polyimide | 日产化学工业株式会社 | 2020-04-03 | — | — | CN | disclosed |
| CN-110903286-A | 4, 6-disubstituted pyridine [3,2-d ] pyrimidine compound and preparation and application thereof | 沈阳药科大学 | 2020-03-24 | — | — | CN | disclosed |
| US-4131738-A | 6-Hydroxy-PGE1 compounds | THE UPJOHN COMPANY (US) | 1978-12-26 | — | — | US | disclosed |
| US-4128713-A | 6,7-Didehydro-PGI1 compounds | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | disclosed |
| US-4126744-A | PROSTACYCLIN, MUSCLE STIMULANTS, PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1978-11-21 | — | — | US | disclosed |
| US-4112224-A | PROSTAGLANDIN | THE UPJOHN COMPANY (US) | 1978-09-05 | — | — | US | disclosed |
| US-4109082-A | PROSTACYCLIN ANALOGS; SMOOTH MUSCLE STIMULATORS | THE UPJOHN COMPANY (US) | 1978-08-22 | — | — | US | disclosed |
| US-4100192-A | Inter-phenylene-PG amides | THE UPJOHN COMPANY (US) | 1978-07-11 | — | — | US | disclosed |
| US-4097489-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-06-27 | — | — | US | disclosed |
| US-3959269-A | TRANQUILIZERS, SEDATIVES | SANDOZ, INC. (US) | 1976-05-25 | — | — | US | disclosed |