Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 7/20 | 0.49 |
| ▸ | TDO2 | P48775 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8226202 | 0.83 | MAPT (0.43) | IDO1TDO2MAPTKDM4ETDP1 | |
| SCHEMBL19000599 | 0.76 | IDO1 (0.51) | IDO1TDO2MAPTKDM4ETDP1 | |
| SCHEMBL31073452 | 0.75 | MAPT (0.61) | IDO1TDO2MAPTKDM4ETDP1 | |
| SCHEMBL721134 | 0.74 | KMT2A (0.59) | MAPTMEN1KMT2APOLBGAA | |
| SCHEMBL8195596 | 0.74 | KMT2A (0.59) | MAPTMEN1KMT2APOLBGAA | |
| SCHEMBL24754644 | 0.74 | IDO1 (0.46) | IDO1TDO2MAPTKDM4ETDP1 | |
| SCHEMBL28859743 | 0.74 | IDO1 (0.46) | IDO1TDO2MAPTKDM4ETDP1 | |
| SCHEMBL1491212 | 0.74 | KDM4E (0.47) | IDO1TDO2MAPTKDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL1491278 | 0.73 | KDM4E (0.46) | IDO1TDO2MAPTKDM4ETDP1 | |
| SCHEMBL27693694 | 0.73 | HPGDS (0.54) | IDO1TDO2MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3923905-A1 | LIQUID PHARMACEUTICAL FORMULATIONS OF PTH CONJUGATES | Ascendis Pharma Bone Diseases A/S (DK) | 2021-12-22 | — | — | EP | disclosed |
| CN-113423383-A | Liquid pharmaceutical formulations of PTH conjugates | 阿森迪斯药物骨疾病股份有限公司 | 2021-09-21 | — | — | CN | disclosed |
| WO-2020165087-A1 | LIQUID PHARMACEUTICAL FORMULATIONS OF PTH CONJUGATES | ASCENDIS PHARMA BONE DISEASES A/S (DK) | 2020-08-20 | — | — | WO | disclosed |