SCHEMBL22345285

SCHEMBL22345285

O=C(O)CCC(=O)C[n+]1ccc(-c2ncccn2)cn1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
GAA P10253 1/20 0.36
CYP2C19 P33261 1/20 0.36
SHMT2 P34897 1/20 0.33
FFAR1 O14842 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HIF1A Q16665 1/20 0.33
CYP2A6 P11509 1/20 0.33
NR4A2 P43354 1/20 0.33
CTNNB1 P35222 1/20 0.32
WNT3A P56704 1/20 0.32
POLB P06746 1/20 0.32
KDM4E B2RXH2 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
HPGD P15428 1/20 0.31
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL22345329 1.00 ALDH1A1 (0.36) ALDH1A1GAACYP2C19SHMT2FFAR1
SCHEMBL22345327 0.88 CYP2A6 (0.32) CYP2A6
SCHEMBL20753259 0.87 CYP2A6 (0.35) ALDH1A1SHMT2FFAR1LMNACYP1A2
SCHEMBL30465888 0.87 CYP2A6 (0.35) ALDH1A1SHMT2FFAR1LMNACYP1A2
Hydrochloric Acid SCHEMBL20743429 0.87 CYP2A6 (0.35) ALDH1A1SHMT2FFAR1LMNACYP1A2
Bromide SCHEMBL20743565 0.86 KDM4E (0.36) ALDH1A1SHMT2FFAR1LMNACYP1A2
SCHEMBL24001087 0.85 TBXA2R (0.36) SMN1; SMN2TBXA2R
SCHEMBL20753383 0.84 TBXA2R (0.38) SMN1; SMN2TBXA2R
Sulfuric Acid SCHEMBL28850618 0.83 TSHR (0.33) ALDH1A1CYP2A6CTNNB1WNT3APOLB
Sulfuric Acid SCHEMBL28850656 0.81 TSHR (0.32) ALDH1A1CYP2A6CTNNB1WNT3APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3924347-A1 PYRIDAZINIUM COMPOUNDS FOR USE IN A METHOD OF CONTROLLING UNWANTED PLANT GROWTH Syngenta Crop Protection AG (CH) 2021-12-22 EP disclosed
WO-2020164973-A1 PYRIDAZINIUM COMPOUNDS FOR USE IN A METHOD OF CONTROLLING UNWANTED PLANT GROWTH SYNGENTA CROP PROTECTION AG (CH) 2020-08-20 WO disclosed