Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21343678 | 0.90 | CSNK1D (0.33) | NAMPT | |
| SCHEMBL22345626 | 0.89 | FASN (0.31) | — | |
| SCHEMBL24325242 | 0.87 | GRM5 (0.32) | — | |
| SCHEMBL24325236 | 0.87 | — | — | |
| SCHEMBL24324958 | 0.87 | — | — | |
| SCHEMBL24324818 | 0.86 | GRIN1 (0.31) | — | |
| SCHEMBL24324952 | 0.86 | — | — | |
| SCHEMBL24324688 | 0.86 | CYP3A4 (0.32) | — | |
| SCHEMBL24324947 | 0.86 | BTK (0.31) | — | |
| SCHEMBL22345614 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12250947-B2 | Substituted azaspiro-cycles as herbicides | SYNGENTA CROP PROTECTION AG (CH) | 2025-03-18 | — | — | US | disclosed |
| EP-3924338-B1 | SUBSTITUTED AZASPIRO-CYCLES AS HERBICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2024-03-20 | — | — | EP | disclosed |
| CN-113423692-B | Substituted azaspiro compounds as herbicides | 先正达农作物保护股份公司 | 2024-01-23 | — | — | CN | disclosed |
| US-20220117228-A1 | SUBSTITUTED AZASPIRO-CYCLES AS HERBICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2022-04-21 | — | — | US | disclosed |
| US-20220117228-A1 | SUBSTITUTED AZASPIRO-CYCLES AS HERBICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2022-04-21 | — | — | US | disclosed |
| EP-3924338-A1 | SUBSTITUTED AZASPIRO-CYCLES AS HERBICIDES | Syngenta Crop Protection AG (CH) | 2021-12-22 | — | — | EP | disclosed |
| WO-2020165233-A1 | SUBSTITUTED AZASPIRO-CYCLES AS HERBICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2020-08-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12250947-B2 | Substituted azaspiro-cycles as herbicides | DDT, DHFR, CCNB3 | NAMPT 1440/4885 |
| US-20220117228-A1 | SUBSTITUTED AZASPIRO-CYCLES AS HERBICIDES | DDT, DHFR, CCNB3 | NAMPT 1440/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.