Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29367118 | 0.90 | PDCD1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL5950948 | 0.90 | PDCD1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL216306 | 0.90 | PDCD1 (0.31) | — | |
| SCHEMBL7710139 | 0.87 | PDCD1 (0.31) | — | |
| Fluoride Ion SCHEMBL1130921 | 0.87 | PDCD1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL2234634 | 0.87 | BRD4 (0.31) | — | |
| Hydrochloric Acid SCHEMBL30203909 | 0.87 | BRD4 (0.31) | — | |
| Hydrochloric Acid SCHEMBL8457636 | 0.86 | KDR (0.32) | — | |
| Hydrochloric Acid SCHEMBL8461611 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL30525927 | 0.83 | GSTP1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799726-B1 | TRIALKYLALUMINUM TREATED SUPPORTS | EXXONMOBIL CHEM PATENTS INC (US) | 2011-07-13 | — | — | EP | claimed |
| US-7741417-B2 | Preparation of polymerization catalyst activators utilizing indole-modified silica supports | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-06-22 | — | — | US | claimed |
| US-7385015-B2 | Trialkylaluminum treated supports | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2008-06-10 | — | — | US | claimed |
| EP-1799726-A1 | TRIALKYLALUMINUM TREATED SUPPORTS | Exxonmobil Chemical Patents Inc. (US) | 2007-06-27 | — | — | EP | claimed |
| US-7220695-B2 | Supported activator | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-05-22 | — | — | US | claimed |
| US-20070055028-A1 | Preparation of polymerization catalyst activators utilizing indole-modified silica supports | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-03-08 | — | — | US | claimed |
| WO-2006044058-A1 | TRIALKYLALUMINUM TREATED SUPPORTS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-04-27 | — | — | WO | claimed |
| US-10676547-B2 | Aluminum alkyls with pendant olefins on clays | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2020-06-09 | — | — | US | disclosed |
| EP-2064248-B1 | PREPARATION OF POLYMERIZATION CATALYST ACTIVATORS UTILIZING INDOLE-MODIFIED SILICA SUPPORTS | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2018-10-10 | — | — | EP | disclosed |
| US-20180201700-A1 | Aluminum Alkyls with Pendant Olefins on Clays | EXXONMOBIL CHEMICAL PATENTS INC. | 2018-07-19 | — | — | US | disclosed |
| EP-1709085-B1 | SUPPORTED ACTIVATOR FOR POLYMERISATION CATALYST | EXXONMOBIL CHEM PATENTS INC (US) | 2013-03-20 | — | — | EP | disclosed |
| EP-1799726-B1 | TRIALKYLALUMINUM TREATED SUPPORTS | EXXONMOBIL CHEM PATENTS INC (US) | 2011-07-13 | — | — | EP | disclosed |
| US-7741417-B2 | Preparation of polymerization catalyst activators utilizing indole-modified silica supports | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-06-22 | — | — | US | disclosed |
| EP-2064248-A1 | PREPARATION OF POLYMERIZATION CATALYST ACTIVATORS UTILIZING INDOLE-MODIFIED SILICA SUPPORTS | ExxonMobil Chemical Patents Inc. (US) | 2009-06-03 | — | — | EP | disclosed |
| WO-2008027116-A1 | PREPARATION OF POLYMERIZATION CATALYST ACTIVATORS UTILIZING INDOLE-MODIFIED SILICA SUPPORTS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2008-03-06 | — | — | WO | disclosed |
| EP-1799726-A1 | TRIALKYLALUMINUM TREATED SUPPORTS | Exxonmobil Chemical Patents Inc. (US) | 2007-06-27 | — | — | EP | disclosed |
| US-7220695-B2 | Supported activator | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-05-22 | — | — | US | disclosed |
| US-20070055028-A1 | Preparation of polymerization catalyst activators utilizing indole-modified silica supports | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-03-08 | — | — | US | disclosed |
| WO-2006044058-A1 | TRIALKYLALUMINUM TREATED SUPPORTS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2006-04-27 | — | — | WO | disclosed |