SCHEMBL22345884

SCHEMBL22345884

O=C(O)c1cc2ccc3cccc4cc(C(=O)O)c(c1)c2c34

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.73
MEN1 O00255 4/20 0.73
PTPN1 P18031 1/20 0.51
HSD17B10 Q99714 4/20 0.44
PLA2G2D Q9UNK4 1/20 0.44
GRIN2D O15399 1/20 0.44
GRIN2A Q12879 1/20 0.44
GRIN2B Q13224 1/20 0.44
GRIN2C Q14957 1/20 0.44
ALDH1A1 P00352 4/20 0.43
KDM4E B2RXH2 3/20 0.43
HPGD P15428 3/20 0.43
CYP1A2 P05177 2/20 0.43
GLA P06280 1/20 0.43
POLB P06746 1/20 0.43
CYP2D6 P10635 1/20 0.43
NR4A1 P22736 1/20 0.42
NR4A2 P43354 1/20 0.42
NR4A3 Q92570 1/20 0.42
RXFP1 Q9HBX9 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10478169 0.86 KMT2A (0.60) KMT2AMEN1PTPN1HSD17B10GRIN2D
SCHEMBL1901737 0.86 MEN1 (1.00) KMT2AMEN1PTPN1HSD17B10ALDH1A1
SCHEMBL1551182 0.81 KMT2A (0.63) KMT2AMEN1PTPN1HSD17B10ALDH1A1
SCHEMBL19177661 0.79 NR4A1 (0.53) KMT2AMEN1PTPN1HSD17B10GRIN2D
SCHEMBL9312437 0.79 KMT2A (0.56) KMT2AMEN1PTPN1HSD17B10GRIN2D
SCHEMBL28682524 0.79 MEN1 (0.51) KMT2AMEN1PTPN1HSD17B10GRIN2D
SCHEMBL2535448 0.78 KMT2A (0.55) KMT2AMEN1PTPN1HSD17B10GRIN2D
SCHEMBL183076 0.78 KMT2A (0.55) KMT2AMEN1PTPN1HSD17B10GRIN2D
SCHEMBL1403567 0.78 MEN1 (0.82) KMT2AMEN1HSD17B10ALDH1A1KDM4E
SCHEMBL28910870 0.77 NR4A1 (0.55) KMT2AMEN1PTPN1HSD17B10GRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020165882-A2 METHOD OF PRODUCING HIGH-PURITY 2-PYRONE-4,6-DICARBOXYLIC ACID AND METHOD OF PRODUCING INTERMEDIATE FOR SAME 한국화학연구원 2020-08-20 WO claimed