Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | LDHA | P00338 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28891978 | 0.85 | KDM4E (0.49) | KMT2AMEN1LDHAHSD17B10KDM4E | |
| SCHEMBL10478169 | 0.84 | KMT2A (0.60) | KMT2AMEN1LDHAHSD17B10KDM4E | |
| SCHEMBL183076 | 0.83 | KMT2A (0.55) | KMT2AMEN1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL21972844 | 0.81 | KMT2A (0.41) | KMT2AMEN1LDHAHSD17B10KDM4E | |
| SCHEMBL9312437 | 0.81 | KMT2A (0.56) | KMT2AMEN1LDHAHSD17B10KDM4E | |
| SCHEMBL19177661 | 0.81 | NR4A1 (0.53) | KMT2AMEN1LDHAHSD17B10KDM4E | |
| SCHEMBL21972843 | 0.80 | ALDH1A1 (0.44) | KMT2AMEN1LDHAHSD17B10KDM4E | |
| SCHEMBL29350533 | 0.80 | HSD17B10 (0.64) | KMT2AMEN1LDHAHSD17B10KDM4E | |
| SCHEMBL242958 | 0.80 | HSD17B10 (0.64) | KMT2AMEN1LDHAHSD17B10KDM4E | |
| SCHEMBL17256438 | 0.79 | MEN1 (0.46) | KMT2AMEN1HSD17B10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9790484-B2 | Silica encapsulated biomaterials | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2017-10-17 | — | — | US | disclosed |
| EP-2394980-B1 | AROMATIC AMINO COMPOUND MANUFACTURING METHOD | HODOGAYA CHEMICAL CO LTD (JP) | 2016-12-21 | — | — | EP | disclosed |
| US-9238624-B2 | Method of producing aromatic amino compounds | HODOGAYA CHEMICAL CO., LTD. (JP) | 2016-01-19 | — | — | US | disclosed |
| CN-103917098-A | Silica encapsulated biomaterials | UNIV MINNESOTA | 2014-07-09 | — | — | CN | disclosed |
| US-20140163232-A1 | METHOD OF PRODUCING AROMATIC AMINO COMPOUNDS | HODOGAYA CHEMICAL CO., LTD. (JP) | 2014-06-12 | — | — | US | disclosed |
| US-8735626-B2 | Method of producing aromatic amino compounds | HODOGAYA CHEMICAL CO., LTD. (JP) | 2014-05-27 | — | — | US | disclosed |
| US-20140051144-A1 | SILICA ENCAPSULATED BIOMATERIALS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2014-02-20 | — | — | US | disclosed |
| CN-103347486-A | Whitening agent containing 3-hydroxy-2-pyrone | NICHIREI BIOSCIENCES INC | 2013-10-09 | — | — | CN | disclosed |
| WO-2012116013-A2 | SILICA ENCAPSULATED BIOMATERIALS | WACKETT LAWRENCE P (US) | 2012-08-30 | — | — | WO | disclosed |
| EP-2394980-A1 | AROMATIC AMINO COMPOUND MANUFACTURING METHOD | Hodogaya Chemical Co., Ltd. (JP) | 2011-12-14 | — | — | EP | disclosed |
| CN-102239133-A | Aromatic amino compound manufacturing method | HODOGAYA CHEMICAL CO LTD | 2011-11-09 | — | — | CN | disclosed |
| US-20110257404-A1 | METHOD OF PRODUCING AROMATIC AMINO COMPOUNDS | HODOGAYA CHEMICAL CO., LTD. (JP) | 2011-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140163232-A1 | METHOD OF PRODUCING AROMATIC AMINO COMPOUNDS | DDC, AOC2, AOC3 | KMT2A 846/4885MEN1 3474/4885LDHA 2864/4885 |
| US-20110257404-A1 | METHOD OF PRODUCING AROMATIC AMINO COMPOUNDS | AOC2, AOC3, DDC | KMT2A 1118/4885MEN1 2467/4885LDHA 2018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.