Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.67 |
| ▸ | BCR | P11274 | 1/20 | 0.67 |
| ▸ | LCK | P06239 | 2/20 | 0.63 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.54 |
| ▸ | TUBB | P07437 | 2/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.54 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.54 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.54 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.54 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.54 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.54 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.54 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.54 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.54 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2234712 | 1.00 | ABL1 (0.67) | ABL1BCRLCKTUBB1TUBB4A | |
| SCHEMBL2719693 | 0.85 | TUBB1 (0.65) | ABL1BCRTUBB1TUBB4ATUBB | |
| SCHEMBL2719692 | 0.85 | TUBB1 (0.65) | ABL1BCRTUBB1TUBB4ATUBB | |
| SCHEMBL21980876 | 0.84 | TUBB1 (0.71) | ABL1BCRLCKTUBB1TUBB4A | |
| SCHEMBL21980865 | 0.84 | TUBB1 (0.71) | ABL1BCRLCKTUBB1TUBB4A | |
| SCHEMBL4929169 | 0.83 | TDP1 (0.67) | ABL1BCRLCKTUBB1TUBB4A | |
| SCHEMBL4929178 | 0.83 | TDP1 (0.67) | ABL1BCRLCKTUBB1TUBB4A | |
| SCHEMBL30900517 | 0.81 | CYP1A1 (0.65) | ABL1BCRLCKTUBB1TUBB4A | |
| SCHEMBL19433104 | 0.81 | CYP1A1 (0.65) | ABL1BCRLCKTUBB1TUBB4A | |
| SCHEMBL2979470 | 0.81 | LCK (0.73) | ABL1BCRLCKTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2362226-A1 | Diagnostic method for neurodegenerative diseases based on measurement of SIRT1 levels or activity | The President and Fellows of Harvard College (US) | 2011-08-31 | — | — | EP | disclosed |