Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 3/20 | 0.73 |
| ▸ | ABL1 | P00519 | 1/20 | 0.59 |
| ▸ | BCR | P11274 | 1/20 | 0.59 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.55 |
| ▸ | CDK1 | P06493 | 1/20 | 0.55 |
| ▸ | CDK4 | P11802 | 1/20 | 0.55 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.55 |
| ▸ | CCND1 | P24385 | 1/20 | 0.55 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.53 |
| ▸ | TTR | P02766 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | RGS12 | O14924 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2979473 | 1.00 | LCK (0.73) | LCKABL1BCRCCNB2CDK1 | |
| SCHEMBL13338339 | 0.87 | LCK (0.86) | LCKABL1BCRCCNB2CDK1 | |
| SCHEMBL2512334 | 0.87 | LCK (0.86) | LCKABL1BCRCCNB2CDK1 | |
| SCHEMBL2512336 | 0.87 | LCK (0.86) | LCKABL1BCRCCNB2CDK1 | |
| SCHEMBL23754267 | 0.85 | LCK (1.00) | LCKABL1BCRCCNB2CDK1 | |
| SCHEMBL4742460 | 0.85 | LCK (1.00) | LCKABL1BCRCCNB2CDK1 | |
| SCHEMBL30194225 | 0.85 | LCK (1.00) | LCKABL1BCRCCNB2CDK1 | |
| SCHEMBL3392045 | 0.85 | LCK (0.91) | LCKABL1BCRCCNB2CDK1 | |
| SCHEMBL23754269 | 0.85 | LCK (1.00) | LCKABL1BCRCCNB2CDK1 | |
| SCHEMBL4742462 | 0.85 | LCK (1.00) | LCKABL1BCRCCNB2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1075256-B1 | ARYLHYDROCARBON RECEPTOR LIGAND ANTAGONISTS | INST NAT SANTE RECH MED (FR) | 2003-07-30 | — | — | EP | claimed |
| EP-1075256-A1 | ARYLHYDROCARBON RECEPTOR LIGAND ANTAGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2001-02-14 | — | — | EP | claimed |
| WO-1999056737-A1 | ARYLHYDROCARBON RECEPTOR LIGAND ANTAGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1999-11-11 | — | — | WO | claimed |
| US-20250179435-A1 | METHODS AND COMPOSITIONS RELATING TO HEMATOPOIETIC STEM CELL EXPANSION | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2025-06-05 | — | — | US | disclosed |
| EP-4049665-B1 | METHODS AND COMPOSITIONS RELATING TO HEMATOPOIETIC STEM CELL EXPANSION | CHILDRENS MEDICAL CT CORP (US) | 2025-03-12 | — | — | EP | disclosed |
| EP-3313420-B1 | METHODS AND COMPOSITIONS RELATING TO HEMATOPOIETIC STEM CELL EXPANSION, ENRICHMENT, AND MAINTENANCE | CHILDRENS MEDICAL CT CORP (US) | 2024-03-13 | — | — | EP | disclosed |
| US-11891625-B2 | Methods and compositions relating to hematopoietic stem cell expansion, enrichment, and maintenance | CHILDREN'S MEDICAL CENTER CORPORATION | 2024-02-06 | — | — | US | disclosed |
| EP-4049665-A1 | METHODS AND COMPOSITIONS RELATING TO HEMATOPOIETIC STEM CELL EXPANSION | Children's Medical Center Corporation (US) | 2022-08-31 | — | — | EP | disclosed |
| EP-3429603-B1 | METHODS AND COMPOSITIONS RELATING TO HEMATOPOIETIC STEM CELL EXPANSION | CHILDRENS MEDICAL CENTER (US) | 2021-12-29 | — | — | EP | disclosed |
| US-20200248143-A1 | METHODS AND COMPOSITIONS RELATING TO HEMATOPOIETIC STEM CELL EXPANSION, ENRICHMENT, AND MAINTENANCE | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2020-08-06 | — | — | US | disclosed |
| US-10669528-B2 | Methods and compositions relating to hematopoietic stem cell expansion, enrichment, and maintenance | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2020-06-02 | — | — | US | disclosed |
| US-20090208432-A1 | AH Receptor Antagonists | SYMRISE GMBH & CO., KG (DE) | 2009-08-20 | — | — | US | disclosed |
| US-20090208433-A1 | aryl hydrocarbon receptor (Ah receptor; AhR) antagonists such as 2-benzylidene-5,6-dimethoxy-3H-inden-1-one, used for preventing a translocation of an AhR into a cell nucleus, ultraviolet radiation-induced gene expression or skin damage; cosmetics; sunscreen agents; aldol condensation | SYMRISE GMBH & CO., KG (DE) | 2009-08-20 | — | — | US | disclosed |
| US-20090028804-A1 | AhR mediators | SYMRISE GMBH & CO. KG (DE) | 2009-01-29 | — | — | US | disclosed |
| EP-1954831-A2 | AHR MEDIATOR | Symrise GmbH & Co. KG (DE) | 2008-08-13 | — | — | EP | disclosed |
| US-20070191627-A1 | Stilbene derivatives and their use in medicaments | SZEKERES THOMAS | 2007-08-16 | — | — | US | disclosed |
| WO-2007060256-A2 | AHR MEDIATOR | SYMRISE GMBH & CO. KG (DE) | 2007-05-31 | — | — | WO | disclosed |
| EP-1075256-B1 | ARYLHYDROCARBON RECEPTOR LIGAND ANTAGONISTS | INST NAT SANTE RECH MED (FR) | 2003-07-30 | — | — | EP | disclosed |
| EP-1075256-A1 | ARYLHYDROCARBON RECEPTOR LIGAND ANTAGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2001-02-14 | — | — | EP | disclosed |
| WO-1999056737-A1 | ARYLHYDROCARBON RECEPTOR LIGAND ANTAGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1999-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090208432-A1 | AH Receptor Antagonists | AHR, ARNT, HCAR1 | LCK 3843/4885ABL1 1554/4885BCR 971/4885 |
| US-20200248143-A1 | METHODS AND COMPOSITIONS RELATING TO HEMATOPOIETIC STEM CELL EXPANSION, ENRICHMENT, AND MAINTENANCE | HDAC1, EHMT1, MCL1 | LCK 561/4885ABL1 576/4885BCR 538/4885 |
| US-20070191627-A1 | Stilbene derivatives and their use in medicaments | PTGS2, PTGS1, PTGER2 | LCK 3040/4885ABL1 772/4885BCR 4323/4885 |
| US-20090028804-A1 | AhR mediators | AHR, ARNT, HCAR1 | LCK 3894/4885ABL1 1711/4885BCR 1650/4885 |
| US-10669528-B2 | Methods and compositions relating to hematopoietic stem cell expansion, enrichment, and maintenance | HDAC1, EHMT1, MCL1 | LCK 561/4885ABL1 576/4885BCR 538/4885 |
| US-20090208433-A1 | aryl hydrocarbon receptor (Ah receptor; AhR) antagonists such as 2-benzylidene-5,6-dimethoxy-3H-inden-1-one, used for preventing a translocation of an AhR into a cell nucleus, ultraviolet radiation-induced gene expression or skin damage; cosmetics; sunscreen agents; aldol condensation | AHR, ARNT, AIPL1 | LCK 4583/4885ABL1 4259/4885BCR 993/4885 |
| US-20250179435-A1 | METHODS AND COMPOSITIONS RELATING TO HEMATOPOIETIC STEM CELL EXPANSION | MCL1, HCLS1, KIT | LCK 1961/4885ABL1 43/4885BCR 8/4885 |
| US-11891625-B2 | Methods and compositions relating to hematopoietic stem cell expansion, enrichment, and maintenance | HDAC1, EHMT1, MCL1 | LCK 561/4885ABL1 576/4885BCR 538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.