Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25992981 | 0.92 | NR1H4 (0.50) | NR1H4 | |
| SCHEMBL22354368 | 0.90 | NR1H4 (0.49) | NR1H4 | |
| SCHEMBL29532015 | 0.90 | NR1H4 (0.49) | NR1H4 | |
| SCHEMBL22347308 | 0.84 | NR1H4 (0.54) | NR1H4 | |
| SCHEMBL22347283 | 0.84 | NR1H4 (0.53) | NR1H4 | |
| SCHEMBL22347175 | 0.80 | NR1H4 (0.67) | NR1H4 | |
| SCHEMBL22347347 | 0.79 | MGLL (0.37) | NR1H4 | |
| SCHEMBL29532562 | 0.78 | NR1H4 (0.49) | NR1H4 | |
| SCHEMBL22347653 | 0.78 | NR1H4 (0.49) | NR1H4 | |
| SCHEMBL25992962 | 0.78 | NR1H4 (0.51) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3924336-A1 | SUBSTITUTED BICYCLIC COMPOUNDS AS FARNESOID X RECEPTOR MODULATORS | Bristol-Myers Squibb Company (US) | 2021-12-22 | — | — | EP | disclosed |
| WO-2020168143-A1 | SUBSTITUTED BICYCLIC COMPOUNDS AS FARNESOID X RECEPTOR MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-08-20 | — | — | WO | disclosed |