Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.32 |
| ▸ | P4HB | P07237 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22347745 | 0.86 | NR1H4 (0.34) | NR1H4 | |
| SCHEMBL22348079 | 0.86 | NR1H4 (0.44) | NR1H4 | |
| SCHEMBL22350274 | 0.86 | CCNB2 (0.35) | NR1H4 | |
| SCHEMBL22348757 | 0.84 | PKM (0.43) | HDAC4MEF2D | |
| SCHEMBL22350273 | 0.83 | NR1H4 (0.48) | NR1H4HDAC4MEF2D | |
| SCHEMBL25992144 | 0.77 | MAPT (0.44) | — | |
| SCHEMBL22347911 | 0.74 | PKM (0.49) | HDAC4MEF2D | |
| SCHEMBL22350200 | 0.73 | NR1H4 (0.48) | NR1H4 | |
| SCHEMBL29901055 | 0.73 | NR1H4 (0.48) | NR1H4 | |
| SCHEMBL22350237 | 0.73 | NR1H4 (0.59) | NR1H4HDAC4MEF2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3924329-A2 | SUBSTITUTED AMIDE COMPOUNDS USEFUL AS FARNESOID X RECEPTOR MODULATORS | Bristol-Myers Squibb Company (US) | 2021-12-22 | — | — | EP | disclosed |
| WO-2020168152-A2 | SUBSTITUTED AMIDE COMPOUNDS USEFUL AS FARNESOID X RECEPTOR MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-08-20 | — | — | WO | disclosed |