⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28290553 | 0.96 | TSHR (0.31) | — | |
| SCHEMBL5488527 | 0.78 | — | — | |
| SCHEMBL7129224 | 0.76 | ATM (0.47) | — | |
| SCHEMBL2912701 | 0.76 | ATM (0.47) | — | |
| SCHEMBL30072729 | 0.73 | — | — | |
| SCHEMBL94662 | 0.73 | — | — | |
| SCHEMBL94661 | 0.73 | — | — | |
| SCHEMBL28349553 | 0.73 | HCAR2 (0.44) | — | |
| SCHEMBL21933071 | 0.73 | TSHR (0.44) | — | |
| SCHEMBL28377665 | 0.71 | TSHR (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109608379-A | A kind of-two polyethylene glycol of protein cross agent maleimide-acrylic acid succinimide ester preparation method | 苏州昊帆生物股份有限公司 | 2019-04-12 | — | — | CN | claimed |
| CN-117244109-A | Vascularization device and method for implantable diagnosis and treatment | 威廉马歇莱思大学 | 2023-12-19 | — | — | CN | disclosed |
| CN-113825531-B | Vascularization device and method for implantable diagnosis and treatment | 威廉马歇莱思大学 | 2023-07-25 | — | — | CN | disclosed |
| US-20220143270-A1 | VASCULARIZING DEVICES AND METHODS FOR IMPLANTED DIAGNOSTICS AND THERAPEUTICS | WILLIAM MARSH RICE UNIVERSITY (US) | 2022-05-12 | — | — | US | disclosed |
| EP-3924008-A1 | VASCULARIZING DEVICES AND METHODS FOR IMPLANTED DIAGNOSTICS AND THERAPEUTICS | William Marsh Rice University (US) | 2021-12-22 | — | — | EP | disclosed |
| CN-113825531-A | Vascularization devices and methods for implantable diagnosis and treatment | 威廉马歇莱思大学 | 2021-12-21 | — | — | CN | disclosed |
| WO-2020168327-A1 | VASCULARIZING DEVICES AND METHODS FOR IMPLANTED DIAGNOSTICS AND THERAPEUTICS | WILLIAM MARSH RICE UNIVERSITY (US) | 2020-08-20 | — | — | WO | disclosed |
| CN-109608379-A | A kind of-two polyethylene glycol of protein cross agent maleimide-acrylic acid succinimide ester preparation method | 苏州昊帆生物股份有限公司 | 2019-04-12 | — | — | CN | disclosed |