Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.40 |
| ▸ | ITGAL | P20701 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19146563 | 0.86 | KMT2A (0.52) | KMT2ATSHRRAB9AITGB2ICAM1 | |
| SCHEMBL19146438 | 0.85 | KMT2A (0.52) | KMT2ATSHRRAB9ANPC1ITGB2 | |
| SCHEMBL20385968 | 0.85 | KMT2A (0.52) | KMT2ATSHRRAB9ANPC1ITGB2 | |
| SCHEMBL19146399 | 0.85 | KMT2A (0.51) | KMT2ATSHRRAB9ANPC1ITGB2 | |
| SCHEMBL19145898 | 0.83 | KMT2A (0.55) | KMT2ATSHRRAB9ANPC1KDM4E | |
| SCHEMBL22838012 | 0.81 | KMT2A (0.63) | KMT2ATSHRRAB9ANPC1KDM4E | |
| SCHEMBL19146542 | 0.80 | KMT2A (0.58) | KMT2ATSHRRAB9ANPC1ITGB2 | |
| SCHEMBL19146009 | 0.80 | KMT2A (0.58) | KMT2ATSHRRAB9ANPC1ITGB2 | |
| SCHEMBL16254590 | 0.79 | KMT2A (0.65) | KMT2ATSHRRAB9ANPC1KDM4E | |
| SCHEMBL19146023 | 0.79 | KMT2A (0.57) | KMT2ATSHRRAB9ANPC1ITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10745502-B2 | Polymers for oral care compositions | ISP INVESTMENTS LLC (US) | 2020-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10745502-B2 | Polymers for oral care compositions | SMARCC1, MPO, ARID2 | KMT2A 728/4885TSHR 4264/4885RAB9A 2573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.