⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8627389 | 0.69 | — | — | |
| SCHEMBL25786 | 0.69 | — | — | |
| SCHEMBL618275 | 0.69 | — | — | |
| SCHEMBL409162 | 0.69 | — | — | |
| SCHEMBL8578484 | 0.69 | — | — | |
| SCHEMBL27674882 | 0.67 | — | — | |
| SCHEMBL86002 | 0.67 | — | — | |
| SCHEMBL1259537 | 0.67 | — | — | |
| SCHEMBL28489961 | 0.67 | — | — | |
| SCHEMBL11853677 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896404-A1 | PLEUROMUTILIN DERIVATIVES CONTAINING A HYDROXYAMINO- OR ACYLOXYAMINOCYCLOALKYL GROUP | Nabriva Therapeutics Forschungs GmbH (AT) | 2008-03-12 | — | — | EP | claimed |
| WO-2007000004-A1 | PLEUROMUTILIN DERIVATIVES CONTAINING A HYDROXYAMINO- OR ACYLOXYAMINOCYCLOALKYL GROUP | NABRIVA THERAPEUTICS FORSCHUNGS GMBH (AT) | 2007-01-04 | — | — | WO | claimed |
| EP-1073428-B1 | DIHYDROXYPHENYL DERIVATIVES FOR HEPATOPROTECTION AND TREATMENT OF LIVER DISEASES | CHOONGWAE PHARMA CO LTD (KR) | 2004-10-27 | — | — | EP | claimed |
| EP-1073428-A1 | DIHYDROXYPHENYL DERIVATIVES FOR HEPATOPROTECTION AND TREATMENT OF LIVER DISEASES | Choongwae Pharma Co., Ltd. (KR) | 2001-02-07 | — | — | EP | claimed |
| WO-1999055318-A1 | DIHYDROXYPHENYL DERIVATIVES FOR HEPATOPROTECTION AND TREATMENT OF LIVER DISEASES | CHOONGWAE PHARM. CO., LTD. (KR) | 1999-11-04 | — | — | WO | claimed |
| US-4719231-A | 3-[N-(mercaptoacyl)]amino-4-arylbutanoic acid derivatives and an analgesic agent comprising the same | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1988-01-12 | — | — | US | claimed |
| US-9375397-B2 | Composition comprising gas-filled microcapsules for ultrasound mediated delivery | BRACCO SUISSE S.A. (CH) | 2016-06-28 | — | — | US | disclosed |
| US-20110208115-A1 | Composition Comprising Gas-Filled Microcapsules For Ultrasound Mediated Delivery | BRACCO RESEARCH S.A. (CH) | 2011-08-25 | — | — | US | disclosed |
| EP-1879558-B1 | PHARMACEUTICAL COMPOSITION COMPRISING GAS-FILLED MICROCAPSULES FOR ULTRASOUND MEDIATED DELIVERY | BRACCO RESEARCH SA (CH) | 2010-06-09 | — | — | EP | disclosed |
| US-20090041833-A1 | Composition comprising gas-filled microcapsules for ultrasound mediated delivery | BRACCO RESEARCH S.A. (CH) | 2009-02-12 | — | — | US | disclosed |
| EP-1587523-A4 | MULTIVALENT CONSTRUCTS FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS | BRACCO INT BV (NL) | 2008-10-22 | — | — | EP | disclosed |
| EP-1896404-A1 | PLEUROMUTILIN DERIVATIVES CONTAINING A HYDROXYAMINO- OR ACYLOXYAMINOCYCLOALKYL GROUP | Nabriva Therapeutics Forschungs GmbH (AT) | 2008-03-12 | — | — | EP | disclosed |
| EP-1879558-A1 | PHARMACEUTICAL COMPOSITION COMPRISING GAS-FILLED MICROCAPSULES FOR ULTRASOUND MEDIATED DELIVERY | BRACCO RESEARCH S.A. (CH) | 2008-01-23 | — | — | EP | disclosed |
| US-5290807-A | Antiinflammatory agents | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 1994-03-01 | — | — | US | disclosed |
| US-5180738-A | Angiogenesis Inhibitors | TAKEDA CHEMICAL INDUSTRIES (JP) | 1993-01-19 | — | — | US | disclosed |
| US-5166172-A | Angiogenesis inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-11-24 | — | — | US | disclosed |
| US-5164410-A | Fumagillol derivatives and pharmaceutical compositions thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-11-17 | — | — | US | disclosed |
| EP-0359036-A1 | Fumagillol derivatives | Takeda Chemical Industries, Ltd. (JP) | 1990-03-21 | — | — | EP | disclosed |
| EP-0357061-A1 | Angiogenesis inhibitory agent | Takeda Chemical Industries, Ltd. (JP) | 1990-03-07 | — | — | EP | disclosed |
| US-4719231-A | 3-[N-(mercaptoacyl)]amino-4-arylbutanoic acid derivatives and an analgesic agent comprising the same | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1988-01-12 | — | — | US | disclosed |