Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29535036 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL31571595 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL31571613 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL31571615 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL31571589 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL29534365 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL31571603 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL29949206 | 0.91 | BRD4 (0.33) | — | |
| Hydrochloric Acid SCHEMBL29535279 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL29534975 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461365-B2 | Metallocene complex and polymerization method of olefin | JAPAN POLYPROPYLENE CORPORATION (JP) | 2013-06-11 | — | — | US | disclosed |
| US-8394907-B2 | Polypropylene for injection molding | BASELL POLYOLEFINE GMBH (DE) | 2013-03-12 | — | — | US | disclosed |
| US-8030426-B2 | Propylene polymers | BASELL POLYOLEFINE GMBH (DE) | 2011-10-04 | — | — | US | disclosed |
| US-20110230622-A1 | METALLOCENE COMPLEX AND POLYMERIZATION METHOD OF OLEFIN | JAPAN POLYPROPYLENE CORPORATION (JP) | 2011-09-22 | — | — | US | disclosed |
| EP-2360163-A1 | METALLOCENE COMPLEX AND METHOD FOR POLYMERIZING OLEFIN | Japan Polypropylene Corporation (JP) | 2011-08-24 | — | — | EP | disclosed |
| US-6995279-B2 | Metallocene compounds, processes for the production of olefin polymers using catalysts containing the compounds, and olefin polymers produced by the processes | CHISSO CORPORATION (JP) | 2006-02-07 | — | — | US | disclosed |
| US-20040127731-A1 | Metallocene compounds, processes for the production of olefin polymers using catalysts containing the compounds, and olefin polymers produced by the processes | CHISSO CORPORATION (JP) | 2004-07-01 | — | — | US | disclosed |