Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | PI4KA | P42356 | 4/20 | 0.51 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.51 |
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 0.51 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22352041 | 1.00 | BCHE (0.52) | BCHEPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL22990405 | 0.89 | BCHE (0.54) | BCHEPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL24197388 | 0.87 | ADA (0.53) | BCHEPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL24181624 | 0.87 | ADA (0.53) | BCHEPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL10427715 | 0.86 | BCHE (0.55) | BCHEPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL22524135 | 0.85 | BCHE (0.57) | BCHEPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL23516968 | 0.85 | BCHE (0.57) | BCHEPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL20624631 | 0.85 | BCHE (0.57) | BCHEPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL4745241 | 0.85 | BCHE (0.57) | BCHEPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL13998327 | 0.84 | BCHE (0.56) | BCHEPI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020165600-A1 | BICYCLIC PEPTIDE LIGAND STING CONJUGATES AND USES THEREOF | BICYCLETX LIMITED (GB) | 2020-08-20 | — | — | WO | disclosed |