Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | PI4KA | P42356 | 4/20 | 0.54 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.54 |
| ▸ | PI4K2A | Q9BTU6 | 4/20 | 0.54 |
| ▸ | PI4KB | Q9UBF8 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.52 |
| ▸ | ADA | P00813 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22524135 | 1.00 | BCHE (0.57) | BCHEPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL20624631 | 1.00 | BCHE (0.57) | BCHEPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL23516968 | 1.00 | BCHE (0.57) | BCHEPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL13998327 | 0.89 | BCHE (0.56) | BCHEPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL10427715 | 0.89 | BCHE (0.55) | BCHEPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL22990405 | 0.87 | BCHE (0.54) | BCHEPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL22133234 | 0.87 | BCHE (0.56) | BCHEPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL23800751 | 0.87 | BCHE (0.47) | BCHEPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL13939562 | 0.86 | PI4KA (0.57) | BCHEPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL23094395 | 0.86 | ADA (0.56) | BCHEPI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023250368-A2 | ATXN2 RNA INTERFERENCE AGENTS | ELI LILLY AND COMPANY (US) | 2023-12-28 | — | — | WO | disclosed |
| WO-2023114700-A1 | MAPT RNA INTERFERENCE AGENTS | ELI LILLY AND COMPANY (US) | 2023-06-22 | — | — | WO | disclosed |
| WO-2021046426-A9 | CYCLIC DINUCLEOTIDE STING AGONISTS TETHERED TO A PD-1 OR CTLA-4 ANTIBODIES | SPEROVIE BIOSCIENCES, INC. (US) | 2022-02-17 | — | — | WO | disclosed |
| WO-2021178818-A2 | THERAPEUTIC AGENTS AND CONJUGATES THEREOF | BEIJING XUANYI PHARMASCIENCES CO., LTD. (CN) | 2021-09-10 | — | — | WO | disclosed |
| WO-2021046426-A1 | CYCLIC DINUCLEOTIDE STING AGONISTS TETHERED TO A PD-1 OR CTLA-4 ANTIBODIES | SPEROVIE BIOSCIENCES, INC. (US) | 2021-03-11 | — | — | WO | disclosed |
| WO-2008118879-A2 | ANTIVIRAL COMPOSITIONS COMPRISING 2 COMPOUNDS | ARDEA BIOSCIENCES, INC. (US) | 2008-10-02 | — | — | WO | disclosed |