SCHEMBL22352178

SCHEMBL22352178

Cn1c(N)nc2c(ncn2[C@@H]2OC(COP(=O)(O)O)[C@@H](OP(=O)(O)OC[C@@H]3C[C@@H](O)[C@H](n4cnc5c(N)ncnc54)O3)[C@H]2O)c1=O

nearest known ligand 0.65

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ RNASEL Q05823 14/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24703982 0.91 RNASEL (0.75) RNASEL
SCHEMBL20763258 0.86 RNASEL (0.62) RNASEL
SCHEMBL22352060 0.86 RNASEL (0.65) RNASEL
SCHEMBL21417372 0.86 RNASEL (0.66) RNASEL
SCHEMBL21837529 0.86 RNASEL (0.63) RNASEL
SCHEMBL19186042 0.84 RNASEL (0.69) RNASEL
SCHEMBL18937290 0.84 RNASEL (0.69) RNASEL
SCHEMBL20763096 0.84 P2RY1 (0.65) RNASEL
SCHEMBL20763050 0.84 P2RY1 (0.65) RNASEL
SCHEMBL24771772 0.83 RNASEL (0.56) RNASEL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020165600-A1 BICYCLIC PEPTIDE LIGAND STING CONJUGATES AND USES THEREOF BICYCLETX LIMITED (GB) 2020-08-20 — — WO disclosed
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