Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22811853 | 0.87 | KDM4E (0.43) | KDM4EKMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL13638129 | 0.84 | KMT2A (0.71) | KDM4EKMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL12859088 | 0.82 | ALDH1A1 (0.64) | KDM4EKMT2AMEN1ALDH1A1TDP1 | |
| SCHEMBL23008455 | 0.82 | KDM4E (0.54) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL22030560 | 0.80 | KMT2A (0.40) | KDM4EKMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL15348806 | 0.76 | KDM4E (0.42) | KDM4EKMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL11575106 | 0.76 | — | — | |
| SCHEMBL18177855 | 0.75 | KCNJ1 (0.61) | KDM4EALDH1A1MAPTTDP1MAPK1 | |
| SCHEMBL12850091 | 0.74 | KDM4E (0.37) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL28851969 | 0.74 | KDM4E (0.59) | KDM4EKMT2AMEN1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020165600-A1 | BICYCLIC PEPTIDE LIGAND STING CONJUGATES AND USES THEREOF | BICYCLETX LIMITED (GB) | 2020-08-20 | — | — | WO | disclosed |