SCHEMBL223545

SCHEMBL223545

CC(C)(C)C(N=C=O)N=C=O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
CASP1 P29466 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3810993 0.77
SCHEMBL9914281 0.75
SCHEMBL1335823 0.75
SCHEMBL2545911 0.75
SCHEMBL10898102 0.73
SCHEMBL11018185 0.73
SCHEMBL31414859 0.72
SCHEMBL78328 0.72
SCHEMBL1907962 0.72
SCHEMBL331182 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12509419-B2 Process for the distillation of isocyanates COVESTRO DEUTSCHLAND AG (DE) 2025-12-30 US claimed
CN-114423736-B Method for distilling isocyanates 科思创德国股份有限公司 2025-02-18 CN claimed
EP-4163314-B1 PROCESS FOR THE PREPARATION OF SOLID POLYURETHANE HARDENERS EVONIK OPERATIONS GMBH (DE) 2023-12-06 EP claimed
EP-4163314-A1 PROCESS FOR THE PREPARATION OF SOLID POLYURETHANE HARDENERS Evonik Operations GmbH (DE) 2023-04-12 EP claimed
CN-115926107-A Method for preparing solid polyurethane curing agent 赢创运营有限公司 2023-04-07 CN claimed
US-20230105553-A1 PROCESS FOR PRODUCING SOLID POLYURETHANE CURING AGENTS EVONIK OPERATIONS GMBH (DE) 2023-04-06 US claimed
US-20220380303-A1 PROCESS FOR THE DISTILLATION OF ISOCYANATES COVESTRO DEUTSCHLAND AG (DE) 2022-12-01 US claimed
EP-4038049-A1 PROCESS FOR THE DISTILLATION OF ISOCYANATES Covestro Intellectual Property GmbH & Co. KG (DE) 2022-08-10 EP claimed
CN-114423736-A Method for distilling isocyanates 科思创知识产权两合公司 2022-04-29 CN claimed
WO-2021063760-A1 PROCESS FOR THE DISTILLATION OF ISOCYANATES COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) 2021-04-08 WO claimed
EP-3798208-A1 METHOD FOR DISTILLATION OF ISOCYANATES Covestro Deutschland AG (DE) 2021-03-31 EP claimed
US-12509419-B2 Process for the distillation of isocyanates COVESTRO DEUTSCHLAND AG (DE) 2025-12-30 US disclosed
CN-114423736-B Method for distilling isocyanates 科思创德国股份有限公司 2025-02-18 CN disclosed
US-12152102-B2 Process for producing solid polyurethane curing agents EVONIK OPERATIONS GMBH (DE) 2024-11-26 US disclosed
EP-4163314-B1 PROCESS FOR THE PREPARATION OF SOLID POLYURETHANE HARDENERS EVONIK OPERATIONS GMBH (DE) 2023-12-06 EP disclosed
EP-1103572-A2 Radiation curable isocyanate groups containing urethaneacrylate and its use BAYER AG (DE) 2001-05-30 EP disclosed
EP-1085065-A2 Elastic coating system containing UV-curable urethane(meth)acrylates with isocyanate groups and its use BAYER AG (DE) 2001-03-21 EP disclosed
EP-0928800-A1 Coating system based on UV-curing isocyanate containing urethane methacrylate isocyanates Bayer Aktiengesellschaft (DE) 1999-07-14 EP disclosed
US-5145745-A Anionic polyurethane KONICA CORPORATION (JP) 1992-09-08 US disclosed
EP-0339522-A2 By UV-radiation crosslinkable composition for the preparation of adhering coatings BASF Aktiengesellschaft (DE) 1989-11-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509419-B2 Process for the distillation of isocyanates ACMSD, MRPL9, CA9 TSHR 4417/4885CASP1 3593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.