⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11996977 | 0.68 | — | — | |
| SCHEMBL3105149 | 0.61 | — | — | |
| SCHEMBL4666792 | 0.61 | — | — | |
| SCHEMBL3798075 | 0.51 | — | — | |
| SCHEMBL5416696 | 0.49 | — | — | |
| SCHEMBL1505792 | 0.49 | — | — | |
| SCHEMBL8724658 | 0.48 | — | — | |
| SCHEMBL87368 | 0.47 | — | — | |
| SCHEMBL2703784 | 0.46 | — | — | |
| SCHEMBL24695998 | 0.45 | ADH1A (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3328827-B1 | PRODRUGS OF GLUTAMINE ANALOGS | UNIV JOHNS HOPKINS (US) | 2023-07-05 | — | — | EP | disclosed |
| WO-2020167829-A1 | METHOD OF PREPARING A DON PRODRUG FROM L-PYROGLUTAMIC ACID | DRACEN PHARMACEUTICALS, INC. (US) | 2020-08-20 | — | — | WO | disclosed |