Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22355454 | 1.00 | NTRK1 (0.35) | NTRK1BRD4CREBBP | |
| SCHEMBL22355519 | 1.00 | NTRK1 (0.35) | NTRK1BRD4CREBBP | |
| Hydrochloric Acid SCHEMBL26618555 | 0.98 | NTRK1 (0.34) | NTRK1BRD4CREBBP | |
| Hydrochloric Acid SCHEMBL30850013 | 0.98 | NTRK1 (0.34) | NTRK1BRD4CREBBP | |
| Hydrochloric Acid SCHEMBL29694249 | 0.98 | NTRK1 (0.34) | NTRK1BRD4CREBBP | |
| SCHEMBL22355411 | 0.80 | OPRM1 (0.30) | — | |
| SCHEMBL22355412 | 0.80 | OPRM1 (0.30) | — | |
| SCHEMBL22355462 | 0.80 | KDM4E (0.30) | — | |
| SCHEMBL22355524 | 0.80 | OPRM1 (0.30) | — | |
| SCHEMBL22355460 | 0.80 | KDM4E (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020165776-A1 | HYDROXYPYRIDOXAZEPINES AS NRF2 ACTIVATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-08-20 | — | — | WO | disclosed |