Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 8/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 2/20 | 0.31 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.31 |
| ▸ | OTC | P00480 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22355301 | 0.94 | MAPT (0.47) | MAPTCXCR4MEN1KMT2AALDH1A1 | |
| SCHEMBL22355330 | 0.85 | MAPT (0.42) | MAPTCXCR4MEN1KMT2AALDH1A1 | |
| SCHEMBL13805262 | 0.83 | CXCR4 (0.44) | MAPTCXCR4MEN1KMT2ACHRM2 | |
| SCHEMBL24548858 | 0.83 | CXCR4 (0.53) | MAPTCXCR4MEN1KMT2ACHRM2 | |
| SCHEMBL13805263 | 0.83 | CXCR4 (0.47) | MAPTCXCR4MEN1KMT2ACHRM2 | |
| SCHEMBL22355320 | 0.77 | CXCR4 (0.44) | MAPTCXCR4MEN1KMT2ACHRM2 | |
| SCHEMBL22355347 | 0.77 | SIGMAR1 (0.54) | CXCR4MEN1KMT2AALDH1A1CHRM2 | |
| SCHEMBL22355323 | 0.77 | SIGMAR1 (0.54) | CXCR4MEN1KMT2AALDH1A1CHRM2 | |
| SCHEMBL9041381 | 0.77 | MAPT (0.49) | MAPTCXCR4MEN1KMT2ACHRM2 | |
| SCHEMBL8393831 | 0.77 | MAPT (0.49) | MAPTCXCR4MEN1KMT2ACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3377504-B1 | CYCLAM BASED COMPOUNDS, THEIR CONJUGATES, CO-ORDINATION COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, METHOD OF PREPARATION AND USE THEREOF | UNIV KARLOVA (CZ) | 2020-08-19 | — | — | EP | disclosed |