Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | CDK9 | P50750 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10942647 | 0.79 | POLB (0.67) | POLBTAAR1MAPTALDH1A1MEN1 | |
| SCHEMBL22357458 | 0.79 | POLB (0.61) | POLBTAAR1MAPTALDH1A1MEN1 | |
| SCHEMBL10368145 | 0.78 | POLB (0.59) | POLBTAAR1MAPTALDH1A1MEN1 | |
| SCHEMBL8786423 | 0.76 | POLB (0.57) | POLBTAAR1MAPTALDH1A1MEN1 | |
| SCHEMBL1802214 | 0.76 | TAAR1 (0.79) | POLBTAAR1MAPTALDH1A1MEN1 | |
| SCHEMBL5960486 | 0.76 | TAAR1 (0.79) | POLBTAAR1MAPTALDH1A1MEN1 | |
| SCHEMBL4741417 | 0.76 | TAAR1 (0.79) | POLBTAAR1MAPTALDH1A1MEN1 | |
| SCHEMBL28401398 | 0.76 | POLB (0.56) | POLBTAAR1MAPTALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL8008025 | 0.74 | TAAR1 (0.77) | POLBTAAR1MAPTALDH1A1MEN1 | |
| SCHEMBL4982071 | 0.74 | POLB (0.66) | POLBTAAR1MAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488028-B1 | SUBSTITUTED PIPERIDINES THAT INCREASE P53 ACTIVITY AND THE USES THEREOF | MERCK SHARP & DOHME (US) | 2020-08-19 | — | — | EP | disclosed |