SCHEMBL5960486

SCHEMBL5960486

C[C@@H](N)C(=O)Nc1ccccc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.79
LTA4H P09960 1/20 0.62
ALDH1A1 P00352 4/20 0.61
MAPT P10636 4/20 0.61
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
RXFP1 Q9HBX9 1/20 0.61
POLB P06746 1/20 0.57
XIAP P98170 1/20 0.56
GAA P10253 2/20 0.56
ATM Q13315 2/20 0.56
LMNA P02545 1/20 0.56
NAPRT Q6XQN6 1/20 0.54
HSD17B10 Q99714 1/20 0.54
SMN1; SMN2 Q16637 3/20 0.53
HPGD P15428 2/20 0.53
HTT P42858 2/20 0.53
RAB9A P51151 2/20 0.53
HSP90AA1 P07900 2/20 0.53
NPSR1 Q6W5P4 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4741417 1.00 TAAR1 (0.79) TAAR1LTA4HALDH1A1MAPTMEN1
SCHEMBL1802214 1.00 TAAR1 (0.79) TAAR1LTA4HALDH1A1MAPTMEN1
Hydrochloric Acid SCHEMBL8010453 0.98 TAAR1 (0.77) TAAR1LTA4HALDH1A1MAPTMEN1
Hydrochloric Acid SCHEMBL8008025 0.98 TAAR1 (0.77) TAAR1LTA4HALDH1A1MAPTMEN1
Hydrochloric Acid SCHEMBL1799954 0.98 TAAR1 (0.77) TAAR1LTA4HALDH1A1MAPTMEN1
Bromide SCHEMBL11433754 0.98 TAAR1 (0.77) TAAR1LTA4HALDH1A1MAPTMEN1
SCHEMBL4652086 0.89 TAAR1 (1.00) TAAR1LTA4HALDH1A1MAPTMEN1
SCHEMBL1751436 0.89 TAAR1 (1.00) TAAR1LTA4HALDH1A1MAPTMEN1
SCHEMBL11791805 0.86 ALDH1A1 (0.76) TAAR1LTA4HALDH1A1MAPTMEN1
Bromide SCHEMBL11428373 0.86 TAAR1 (0.61) TAAR1LTA4HALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4734980-A2 TMEM175 AGONISTS, COMPOSITIONS, AND METHODS OF USE Caraway Therapeutics, Inc. (US) 2026-05-06 EP disclosed
WO-2025006726-A2 TMEM175 AGONISTS, COMPOSITIONS, AND METHODS OF USE CARAWAY THERAPEUTICS, INC. (US) 2025-01-02 WO disclosed
WO-2006105996-A2 PROCESS FOR THE PREPARATION OF AN OPTICALLY ACTIVE ESTER DSM IP ASSETS B.V. (NL) 2006-10-12 WO disclosed
EP-1710221-A1 Process for the preparation of an optically active ester DSM IP Assets B.V. (NL) 2006-10-11 EP disclosed