Sugi Predict

Sugi Predict / Compounds / SCHEMBL223582

SCHEMBL223582

SCHEMBL223582

N#Cc1ccc(N2CCCC2C=O)cc1C(F)(F)F

nearest known ligand 0.63

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ AR P10275 16/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL223581 1.00 AR (0.63) AR
SCHEMBL13651258 0.82 AR (0.65) AR
SCHEMBL4904736 0.82 AR (0.65) AR
SCHEMBL22667487 0.82 AR (0.65) AR
SCHEMBL30812514 0.81 AR (0.65) AR
SCHEMBL222331 0.81 AR (0.65) AR
SCHEMBL222330 0.81 AR (0.65) AR
SCHEMBL18997276 0.80 AR (0.63) AR
SCHEMBL4896866 0.80 AR (0.59) AR
SCHEMBL4903955 0.80 AR (0.59) AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024046605-A1 COMPOUNDS FOR THE DETECTION OF LIGANDROL NATIONAL CENTER FOR SCIENTIFIC RESEARCH "DEMOKRITOS" (GR) 2024-03-07 — — WO disclosed
US-11358931-B2 Selective androgen receptor modulators (SARMs) and uses thereof LIGAND PHARMACEUTICALS INCORPORATED (US) 2022-06-14 — — US disclosed
US-20200361866-A1 SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) AND USES THEREOF CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2020-11-19 — — US disclosed
US-10730831-B2 Selective androgen receptor modulators (SARMs) and uses thereof LIGAND PHARMACEUTICALS INCORPORATED (US) 2020-08-04 — — US disclosed
US-20190040006-A1 SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) AND USES THEREOF CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2019-02-07 — — US disclosed
US-10106500-B2 Selective androgen receptor modulators (SARMs) and uses thereof LIGAND PHARMACEUTICALS INCORPORATED (US) 2018-10-23 — — US disclosed
US-20170247325-A1 SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) AND USES THEREOF CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2017-08-31 — — US disclosed
US-9675583-B2 Selective androgen receptor modulators (SARMS) and uses thereof LIGAND PHARMACEUTICALS INCORPORATED (US) 2017-06-13 — — US disclosed
US-20160038461-A1 SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) AND USES THEREOF CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2016-02-11 — — US disclosed
US-9139520-B2 Selective androgen receptor modulators (SARMs) and uses thereof LIGAND PHARMACEUTICALS INCORPORATED (US) 2015-09-22 — — US disclosed
US-8748633-B2 Selective androgen receptor modulators (SARMs) and uses thereof LIGAND PHARMACEUTICALS INCORPORATED (US) 2014-06-10 — — US disclosed
US-20130184206-A1 Selective androgen receptor modulators (SARMs) and uses thereof LIGAND PHARMACEUTICALS INCORPORATED (US) 2013-07-18 — — US disclosed
EP-2222636-B1 SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) AND USES THEREOF LIGAND PHARM INC (US) 2013-04-10 — — EP disclosed
US-8354446-B2 Selective androgen receptor modulators (SARMs) and uses thereof LIGAND PHARMACEUTICALS INCORPORATED (US) 2013-01-15 — — US disclosed
EP-2489656-A1 Selective androgen receptor modulators (sarms) and uses thereof Ligand Pharmaceuticals Inc. (US) 2012-08-22 — — EP disclosed
US-20120004220-A9 SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) AND USES THEREOF CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2012-01-05 — — US disclosed
US-20100256129-A1 SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) AND USES THEREOF LIGAND PHARMACEUTICALS INCORPORATED 2010-10-07 — — US disclosed
EP-2222636-A2 SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) AND USES THEREOF Ligand Pharmaceuticals Inc. (US) 2010-09-01 — — EP disclosed
WO-2009082437-A9 SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) AND USES THEREOF LIGAND PHARMACEUTICALS INCORPORATED (US) 2010-08-12 — — WO disclosed
WO-2009082437-A2 SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) AND USES THEREOF LIGAND PHARMACEUTICALS INCORPORATED (US) 2009-07-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130184206-A1 Selective androgen receptor modulators (SARMs) and uses thereof AR, NR5A1, SHBG AR 1/4885
US-20200361866-A1 SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) AND USES THEREOF AR, NR5A1, SHBG AR 1/4885
US-20100256129-A1 SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) AND USES THEREOF AR, NR5A1, SHBG AR 1/4885
US-11358931-B2 Selective androgen receptor modulators (SARMs) and uses thereof AR, NR5A1, SHBG AR 1/4885
US-20170247325-A1 SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) AND USES THEREOF AR, NR5A1, SHBG AR 1/4885
US-10106500-B2 Selective androgen receptor modulators (SARMs) and uses thereof AR, NR5A1, SHBG AR 1/4885
US-20160038461-A1 SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) AND USES THEREOF AR, NR5A1, SHBG AR 1/4885
US-20190040006-A1 SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) AND USES THEREOF AR, NR5A1, SHBG AR 1/4885
US-10730831-B2 Selective androgen receptor modulators (SARMs) and uses thereof AR, NR5A1, SHBG AR 1/4885
US-20120004220-A9 SELECTIVE ANDROGEN RECEPTOR MODULATORS (SARMS) AND USES THEREOF AR, NR5A1, SHBG AR 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.