Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 13/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 12/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.52 |
| ▸ | USP2 | O75604 | 9/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 6/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27381029 | 0.84 | CYP2D6 (0.55) | CYP2D6CYP3A4CYP1A2USP2ALOX15 | |
| SCHEMBL22358967 | 0.81 | TSHR (0.45) | CYP2D6CYP3A4CYP1A2USP2TSHR | |
| SCHEMBL18212474 | 0.80 | CYP2D6 (0.52) | CYP2D6CYP3A4CYP1A2USP2ALOX15 | |
| SCHEMBL18926698 | 0.80 | CYP2D6 (0.56) | CYP2D6CYP3A4CYP1A2USP2ALOX15 | |
| SCHEMBL17284586 | 0.78 | CYP2D6 (0.46) | CYP2D6CYP3A4CYP1A2USP2ALOX15 | |
| SCHEMBL27381021 | 0.77 | CYP2D6 (0.59) | CYP2D6CYP3A4CYP1A2USP2ALOX15 | |
| SCHEMBL24751941 | 0.77 | CYP3A4 (0.51) | CYP2D6CYP3A4CYP1A2USP2ALOX15 | |
| SCHEMBL13400658 | 0.77 | CYP3A4 (0.51) | CYP2D6CYP3A4CYP1A2USP2ALOX15 | |
| SCHEMBL22794820 | 0.77 | PIK3CD (0.62) | CYP2D6CYP3A4CYP1A2USP2ALOX15 | |
| SCHEMBL29088302 | 0.77 | TSHR (0.60) | CYP2D6CYP3A4CYP1A2USP2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020167518-A1 | BIFUNCTIONAL COMPOUNDS FOR DEGRADING BTK VIA UBIQUITIN PROTEOSOME PATHWAY | NURIX THERAPEUTICS, INC. (US) | 2020-08-20 | — | — | WO | disclosed |