Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 18/20 | 0.74 |
| ▸ | ADORA1 | P30542 | 18/20 | 0.74 |
| ▸ | ADORA2B | P29275 | 14/20 | 0.74 |
| ▸ | ADORA3 | P0DMS8 | 9/20 | 0.74 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28455573 | 0.87 | ADORA2A (0.76) | ADORA2AADORA1ADORA2BADORA3HSP90B1 | |
| SCHEMBL31061536 | 0.85 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BADORA3HSP90AA1 | |
| SCHEMBL1965296 | 0.85 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BADORA3HSP90B1 | |
| SCHEMBL22359199 | 0.82 | ADORA2A (0.55) | ADORA2AADORA1ADORA2BADORA3HSP90B1 | |
| SCHEMBL987368 | 0.82 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BADORA3HSP90AA1 | |
| SCHEMBL4742892 | 0.82 | ADORA2A (0.69) | ADORA2AADORA1ADORA2BADORA3HSP90B1 | |
| SCHEMBL1755068 | 0.80 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BADORA3 | |
| SCHEMBL22359153 | 0.77 | ADORA2A (0.59) | ADORA2AADORA1ADORA2BADORA3HSP90B1 | |
| SCHEMBL30503500 | 0.77 | ADORA2A (0.59) | ADORA2AADORA1ADORA2BADORA3HSP90B1 | |
| SCHEMBL23885221 | 0.77 | ADORA2A (0.69) | ADORA2AADORA1ADORA2BADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020168017-A1 | COMPOSITIONS CONTAINING, METHODS AND USES OF ANTIBODY-TLR AGONIST CONJUGATES | AMBRX, INC. (US) | 2020-08-20 | — | — | WO | disclosed |