Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.59 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.54 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.54 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.54 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.54 |
| ▸ | PI4KA | P42356 | 1/20 | 0.52 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.52 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.52 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.52 |
| ▸ | FBP1 | P09467 | 1/20 | 0.48 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22359153 | 1.00 | ADORA2A (0.59) | ADORA2AADORA2BADORA1TLR7TLR8 | |
| SCHEMBL23421856 | 0.83 | ADORA2A (0.52) | ADORA2AADORA2BADORA1ERBB2HSP90AA1 | |
| SCHEMBL23421471 | 0.83 | ADORA2A (0.51) | ADORA2AADORA2BADORA1ERBB2HSP90AA1 | |
| SCHEMBL23421572 | 0.81 | ADORA2A (0.49) | ADORA2AADORA2BADORA1TLR7ERBB2 | |
| SCHEMBL22359199 | 0.80 | ADORA2A (0.55) | ADORA2AADORA2BADORA1PI4KAPI4K2B | |
| SCHEMBL26348164 | 0.80 | TLR7 (0.54) | TLR7TLR8HSP90AA1HSP90AB1 | |
| SCHEMBL29475714 | 0.80 | TLR7 (0.54) | TLR7TLR8HSP90AA1HSP90AB1 | |
| SCHEMBL22359349 | 0.77 | ERBB2 (0.43) | ADORA2AADORA2BADORA1TLR7TLR8 | |
| SCHEMBL22347080 | 0.77 | TLR7 (0.48) | ADORA2AADORA2BADORA1TLR7ERBB2 | |
| SCHEMBL22359367 | 0.77 | ADORA2A (0.74) | ADORA2AADORA2BADORA1HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119455003-A | Compositions, methods and uses comprising antibody-TLR agonist conjugates | AMBRX公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-119455004-A | Compositions, methods and uses comprising antibody-TLR agonist conjugates | AMBRX公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-113660957-B | Compositions, methods and uses comprising antibody-TLR agonist conjugates | AMBRX公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-116457023-A | antibody-TLR agonist conjugates, methods and uses thereof | AMBRX公司 | 2023-07-18 | — | — | CN | disclosed |