Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 9/20 | 0.46 |
| ▸ | MMP2 | P08253 | 7/20 | 0.42 |
| ▸ | MMP9 | P14780 | 7/20 | 0.42 |
| ▸ | MMP8 | P22894 | 7/20 | 0.42 |
| ▸ | MMP13 | P45452 | 7/20 | 0.42 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22473788 | 0.92 | DGAT1 (0.51) | DGAT1MMP2MMP9MMP8MMP13 | |
| SCHEMBL22473766 | 0.91 | DGAT1 (0.50) | DGAT1MMP2MMP9MMP8MMP13 | |
| SCHEMBL22473628 | 0.91 | DGAT1 (0.50) | DGAT1MMP2MMP9MMP8MMP13 | |
| SCHEMBL18751726 | 0.86 | DGAT1 (0.48) | DGAT1MMP2MMP9MMP8MMP13 | |
| SCHEMBL18751731 | 0.83 | DGAT1 (0.53) | DGAT1MMP2MMP9MMP8MMP13 | |
| SCHEMBL22473778 | 0.82 | DGAT1 (0.60) | DGAT1MMP2MMP9MMP8MMP13 | |
| SCHEMBL22473625 | 0.81 | DGAT1 (0.59) | DGAT1MMP2MMP9MMP8MMP13 | |
| SCHEMBL22473667 | 0.81 | DGAT1 (0.49) | DGAT1MMP2MMP9MMP8MMP13 | |
| SCHEMBL21100148 | 0.81 | DGAT1 (0.44) | DGAT1MMP2MMP9MMP8MMP13 | |
| SCHEMBL19704939 | 0.81 | DGAT1 (0.44) | DGAT1MMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020168172-A1 | CONJUGATE COMPOUNDS FOR THE DEGRADATION OF RAF | ZAMBONI CHEM SOLUTIONS INC. (CA) | 2020-08-20 | — | — | WO | disclosed |