Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 14/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2237417 | 0.99 | BDKRB1 (0.38) | BDKRB1MEN1KMT2AALDH1A1MAPT | |
| Trifluoroacetic Acid SCHEMBL2242040 | 0.96 | BDKRB1 (0.40) | BDKRB1MEN1KMT2AALDH1A1MAPT | |
| Trifluoroacetic Acid SCHEMBL2243351 | 0.95 | BDKRB1 (0.39) | BDKRB1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL12346731 | 0.95 | BDKRB1 (0.41) | BDKRB1MEN1KMT2APKM | |
| SCHEMBL12346734 | 0.94 | BDKRB1 (0.42) | BDKRB1MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL2236213 | 0.93 | BDKRB1 (0.40) | BDKRB1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL12346738 | 0.91 | BDKRB1 (0.43) | BDKRB1MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL2239467 | 0.91 | BDKRB1 (0.49) | BDKRB1ALDH1A1KDM4E | |
| SCHEMBL12346739 | 0.89 | BDKRB1 (0.42) | BDKRB1MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL2240559 | 0.89 | BDKRB1 (0.50) | BDKRB1MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140073627-A1 | BRADYKININ B1 ANTAGONISTS | EVOTEC AG (DE) | 2014-03-13 | — | — | US | claimed |
| US-20110201589-A1 | NEW BRADYKININ B1 ANTAGONISTS | EVOTEC AG (DE) | 2011-08-18 | — | — | US | claimed |
| US-20140073627-A1 | BRADYKININ B1 ANTAGONISTS | EVOTEC AG (DE) | 2014-03-13 | — | — | US | disclosed |
| US-8623859-B2 | Bradykinin B1 antagonists | EVOTEC AG (DE) | 2014-01-07 | — | — | US | disclosed |
| US-20110201589-A1 | NEW BRADYKININ B1 ANTAGONISTS | EVOTEC AG (DE) | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140073627-A1 | BRADYKININ B1 ANTAGONISTS | BDKRB1, BDKRB2, BRS3 | BDKRB1 1/4885MEN1 231/4885KMT2A 1859/4885 |
| US-20110201589-A1 | NEW BRADYKININ B1 ANTAGONISTS | BDKRB1, BDKRB2, BRS3 | BDKRB1 1/4885MEN1 349/4885KMT2A 2057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.