Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18281478 | 0.86 | MEN1 (0.65) | TSHRMAPTMAPK1MEN1HPGD | |
| SCHEMBL679125 | 0.84 | TSHR (0.69) | TSHRMAPTMAPK1HPGDHSD17B10 | |
| SCHEMBL18296815 | 0.84 | KMT2A (0.44) | TSHRMAPTMAPK1MEN1HPGD | |
| Hydrochloric Acid SCHEMBL7130171 | 0.83 | TSHR (0.67) | TSHRMAPTMAPK1HPGDHSD17B10 | |
| SCHEMBL11190983 | 0.81 | SMN1; SMN2 (0.62) | MAPTMAPK1MEN1HPGDKMT2A | |
| SCHEMBL7000095 | 0.81 | KDM4E (0.67) | TSHRMAPTMAPK1MEN1HPGD | |
| SCHEMBL9863061 | 0.80 | KMT2A (0.54) | TSHRMAPK1MEN1HPGDKMT2A | |
| SCHEMBL27698421 | 0.79 | HPGD (0.50) | TSHRMAPK1MEN1HPGDKMT2A | |
| SCHEMBL18661946 | 0.79 | CDC25B (0.47) | TSHRMAPTMAPK1MEN1HPGD | |
| SCHEMBL22363332 | 0.79 | FABP4 (0.53) | MAPTMEN1HPGDKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10752598-B2 | Aryldiazepine derivatives as RSV inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2020-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10752598-B2 | Aryldiazepine derivatives as RSV inhibitors | AHR, FURIN, CYP3A5 | TSHR 2567/4885MAPT 3156/4885MAPK1 2761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.