Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30643518 | 0.92 | HSD17B10 (0.54) | TDP1USP2HSD17B10LMNAALDH1A1 | |
| SCHEMBL204443 | 0.92 | HSD17B10 (0.54) | TDP1USP2HSD17B10LMNAALDH1A1 | |
| Isopropyl Alcohol SCHEMBL7787253 | 0.92 | USP2 (0.52) | TDP1USP2HSD17B10LMNAALDH1A1 | |
| Isobutane SCHEMBL27997158 | 0.92 | USP2 (0.52) | TDP1USP2HSD17B10LMNAALDH1A1 | |
| SCHEMBL10093799 | 0.90 | HSD17B10 (0.52) | TDP1USP2HSD17B10LMNAALDH1A1 | |
| Ethane SCHEMBL2303498 | 0.88 | USP2 (0.54) | TDP1USP2HSD17B10LMNAALDH1A1 | |
| Methyl Alcohol SCHEMBL27869223 | 0.88 | USP2 (0.54) | TDP1USP2HSD17B10LMNAALDH1A1 | |
| SCHEMBL1638881 | 0.88 | LMNA (0.53) | TDP1USP2HSD17B10LMNAALDH1A1 | |
| SCHEMBL30754 | 0.88 | LMNA (0.53) | TDP1USP2HSD17B10LMNAALDH1A1 | |
| Propylene Glycol SCHEMBL8592122 | 0.87 | USP2 (0.50) | TDP1USP2HSD17B10LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4349187-A1 | FILTER WITH ADDED LIQUID, FLAVOR INHALATION ARTICLE EQUIPPED WITH SAID FILTER, AND FLAVOR INHALATION ARTICLE PACKAGE | Japan Tobacco, Inc. (JP) | 2024-04-10 | — | — | EP | disclosed |
| US-20240074490-A1 | FILTER WITH ADDED LIQUID, FLAVOR INHALATION ARTICLE EQUIPPED WITH SAID FILTER, AND FLAVOR INHALATION ARTICLE PACKAGE | JAPAN TOBACCO INC. (JP) | 2024-03-07 | — | — | US | disclosed |
| CN-105979929-B | Composition in the form of an emulsion | 莱雅公司 | 2020-08-21 | — | — | CN | disclosed |
| CN-105722496-B | Fatty acid esters or liquid alkylpolyglucosides containing sugars with HLB <8 and C8-C18Two-phase compositions of branched alkanes | 莱雅公司 | 2020-04-28 | — | — | CN | disclosed |
| EP-3108878-A2 | ANTIMICROBIAL COMPOSITIONS AND METHODS | 3M Innovative Properties Company (US) | 2016-12-28 | — | — | EP | disclosed |
| US-20150320589-A1 | HEATING TOOL | KOBAYASHI PHARMACEUTICAL CO., LTD. (JP) | 2015-11-12 | — | — | US | disclosed |
| EP-2353587-A2 | Antimicrobial compositions and methods | 3M Innovative Properties Co. (US) | 2011-08-10 | — | — | EP | disclosed |
| EP-1460899-A4 | LIQUID COMPOSITIONS OF IPBC IN POLYETHYLENE GLYCOL, POLYPROPYLENE GLYCOL OR POLYPROPYLENE GLYCOL GLYCERYL ESTERS | ISP INVESTMENTS INC (US) | 2005-01-19 | — | — | EP | disclosed |
| EP-1460899-A1 | LIQUID COMPOSITIONS OF IPBC IN POLYETHYLENE GLYCOL, POLYPROPYLENE GLYCOL OR POLYPROPYLENE GLYCOL GLYCERYL ESTERS | ISP INVESTMENTS INC. (US) | 2004-09-29 | — | — | EP | disclosed |
| US-6616740-B2 | 3-iodo-2-propynyl butylcarbamate; do not contribute to the VOC of paints and coatings and is stabilized effectively against discoloration even at elevated temperatures or direct sunlight. | ISP INVESTMENTS INC. | 2003-09-09 | — | — | US | disclosed |
| WO-2003049543-A1 | LIQUID COMPOSITIONS OF IPBC IN POLYETHYLENE GLYCOL, POLYPROPYLENE GLYCOL OR POLYPROPYLENE GLYCOL GLYCERYL ESTERS | ISP INVESTMENTS INC. (US) | 2003-06-19 | — | — | WO | disclosed |
| US-20030109598-A1 | Liquid compositions of IPBC in polyethylene glycol, polypropylene glycol or polypropylene glycol glyceryl esters | ISP INVESTMENTS INC. | 2003-06-12 | — | — | US | disclosed |
| CN-1107716-C | Concentrated stable fabric softening compositions comprising chelants | PROCTER & GAMBLE (US) | 2003-05-07 | — | — | CN | disclosed |
| CN-1098350-C | Fabric softening compound/composition | PROCTER & GAMBLE (US) | 2003-01-08 | — | — | CN | disclosed |
| CN-1272133-A | Concentrated, stable, preferably clear, fabric softening compositions containing amine fabric softeners | PROCTER & GAMBLE (US) | 2000-11-01 | — | — | CN | disclosed |
| US-6110452-A | BACTERICIDES AND ANTISTICKING COATINGS FOR SUBMERGIBLE AGENTS USING POLYGLYCOL FATTY ACID ESTER OR DIESTER | BUCKMAN LABORATORIES INTERNATIONAL INC (US) | 2000-08-29 | — | — | US | disclosed |
| EP-0854842-A1 | METHODS AND COMPOSITIONS FOR CONTROLLING BIOFOULING USING POLYGLYCOL FATTY ACID ESTERS | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 1998-07-29 | — | — | EP | disclosed |
| WO-1997011912-A1 | METHODS AND COMPOSITIONS FOR CONTROLLING BIOFOULING USING POLYGLYCOL FATTY ACID ESTERS | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 1997-04-03 | — | — | WO | disclosed |
| WO-1996014850-A1 | DECOLORIZED CAROTENOID-CYCLODEXTRIN COMPLEXES | NUTRITECH, INC. (US) | 1996-05-23 | — | — | WO | disclosed |
| WO-1995013047-A1 | DECOLORIZED CAROTENOID-CYCLODEXTRIN COMPLEXES | SCHWARTZ JOEL L (US) | 1995-05-18 | — | — | WO | disclosed |