Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | PNP | P00491 | 2/20 | 0.41 |
| ▸ | STING1 | Q86WV6 | 4/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | HINT1 | P49773 | 1/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | TK1 | P04183 | 1/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20610987 | 0.79 | ADORA3 (0.49) | ADORA3PNPSTING1PDE3BPDE3A | |
| SCHEMBL15070724 | 0.79 | ADORA3 (0.49) | ADORA3PNPSTING1PDE3BPDE3A | |
| SCHEMBL20879526 | 0.78 | STING1 (0.45) | ADORA3PNPSTING1PDE3BPDE3A | |
| SCHEMBL18479998 | 0.78 | ADORA3 (0.48) | ADORA3PNPSTING1PDE3BPDE3A | |
| SCHEMBL18477700 | 0.78 | ADORA3 (0.48) | ADORA3PNPSTING1PDE3BPDE3A | |
| SCHEMBL18477854 | 0.78 | ADORA3 (0.48) | ADORA3PNPSTING1PDE3BPDE3A | |
| SCHEMBL15966105 | 0.76 | STING1 (0.49) | ADORA3STING1PDE3BPDE3AHINT1 | |
| SCHEMBL12832017 | 0.76 | ADORA3 (0.48) | ADORA3PNPSTING1PDE3BPDE3A | |
| SCHEMBL18879836 | 0.76 | ADORA3 (0.46) | ADORA3PNPSTING1PDE3BPDE3A | |
| SCHEMBL18477720 | 0.76 | ADORA3 (0.46) | ADORA3PNPSTING1PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE48171-E1 | Substituted nucleosides, nucleotides and analogs thereof | Janssen Biopharma, Inc. (US) | 2020-08-25 | — | — | US | disclosed |