Phosphoramidic Acid

Phosphoramidic Acid

SCHEMBL2236407

CCCCn1ccnc1.CCCCn1ccnc1.NP(=O)(O)O

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 11/20 0.64
FDPS P14324 4/20 0.51
QPCT Q16769 1/20 0.50
MAPK1 P28482 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
EGLN3 Q9H6Z9 1/20 0.46
HTT P42858 1/20 0.45
BTN3A1 O00481 1/20 0.45
CA12 O43570 1/20 0.45
GGPS1 O95749 1/20 0.45
CA2 P00918 1/20 0.45
LMNA P02545 1/20 0.45
MMP2 P08253 1/20 0.45
MMP9 P14780 1/20 0.45
MMP8 P22894 1/20 0.45
MMP14 P50281 1/20 0.45
CA9 Q16790 1/20 0.45
CA14 Q9ULX7 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL28028750 0.93 TBXAS1 (0.68) TBXAS1FDPSQPCTMAPK1SMN1; SMN2
SCHEMBL5289567 0.90 TBXAS1 (0.64) TBXAS1FDPSQPCTMAPK1SMN1; SMN2
Phosphoric Acid SCHEMBL29074288 0.88 TBXAS1 (0.77) TBXAS1FDPSQPCTMAPK1SMN1; SMN2
Phosphoric Acid SCHEMBL29193982 0.87 TBXAS1 (0.80) TBXAS1FDPSMAPK1SMN1; SMN2HTT
Phosphoric Acid SCHEMBL29194112 0.87 TBXAS1 (0.80) TBXAS1FDPSMAPK1SMN1; SMN2HTT
Phosphoric Acid SCHEMBL28028801 0.87 TBXAS1 (0.80) TBXAS1FDPSMAPK1SMN1; SMN2HTT
Phosphoric Acid SCHEMBL29193958 0.87 TBXAS1 (0.80) TBXAS1FDPSMAPK1SMN1; SMN2HTT
SCHEMBL31154488 0.86 TBXAS1 (0.58) TBXAS1FDPSQPCTMAPK1SMN1; SMN2
SCHEMBL81565 0.86
SCHEMBL2593831 0.85 TBXAS1 (0.72) TBXAS1FDPSQPCTMAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2193204-B1 COMPOSITIONS COMPRISING LIPOPHOSPHORAMIDES AND THEIR USES IN GENE THERAPY UNIV BRETAGNE OCCIDENTALE (FR) 2011-08-31 EP disclosed
EP-2193204-A2 NOVEL LIPOPHILIC COMPOSITIONS AND USES THEREOF Universite de Bretagne Occidentale (FR) 2010-06-09 EP disclosed
WO-2009050372-A2 NOVEL LIPOPHILIC COMPOSITIONS AND USES THEREOF UNIVERSITE DE BRETAGNE OCCIDENTALE (FR) 2009-04-23 WO disclosed