Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.41 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2235945 | 0.90 | BCL9 (0.65) | BCL9CTNNB1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL2235137 | 0.87 | BCL9 (0.56) | BCL9CTNNB1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL2233848 | 0.85 | HTR2A (0.50) | BCL9CTNNB1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL2236491 | 0.84 | HTR2A (0.52) | BCL9CTNNB1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL12342249 | 0.82 | HTR2A (0.46) | BCL9CTNNB1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL2235730 | 0.80 | SMN1; SMN2 (0.47) | KMT2AMAPTSMN1; SMN2HTR2ARAB9A | |
| SCHEMBL2232985 | 0.80 | ALDH1A1 (0.46) | BCL9CTNNB1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL21097658 | 0.80 | BCL9 (0.56) | BCL9CTNNB1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL21097204 | 0.80 | BCL9 (0.56) | BCL9CTNNB1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL12375535 | 0.80 | BCL9 (0.56) | BCL9CTNNB1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015137680-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING STROKE AND SYSTEMIC EMBOLISM | 동아에스티 주식회사 | 2015-09-17 | — | — | WO | disclosed |
| US-20110213143-A1 | COMPOUND HAVING TAFIA INHIBITORY ACTIVITY | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2011-09-01 | — | — | US | disclosed |
| EP-2361910-A1 | COMPOUND HAVING TAFIA INHIBITORY ACTIVITY | Taisho Pharmaceutical Co., Ltd. (JP) | 2011-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110213143-A1 | COMPOUND HAVING TAFIA INHIBITORY ACTIVITY | TAF1, TAF5, TAF11 | BCL9 2611/4885CTNNB1 4803/4885KMT2A 3664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.