SCHEMBL2236600

SCHEMBL2236600

CCOP(=O)(CC(=O)OC)OC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.44
PPARD Q03181 2/20 0.43
POLB P06746 1/20 0.39
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
HSD17B10 Q99714 2/20 0.35
ALDH1A1 P00352 1/20 0.35
GAA P10253 3/20 0.34
MGAM O43451 2/20 0.34
SI P14410 2/20 0.34
MGAM2 Q2M2H8 2/20 0.34
TP53 P04637 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
MEN1 O00255 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL337596 0.91 TSHR (0.48) TSHRPPARDPOLBCA12CA1
SCHEMBL28862969 0.89 TSHR (0.46) TSHRPPARDPOLBCA12CA1
SCHEMBL2238293 0.86 TSHR (0.43) TSHRPPARDHSD17B10ALDH1A1GAA
SCHEMBL991 0.84 TSHR (0.46) TSHRPOLBCA12HSD17B10ALDH1A1
SCHEMBL2242177 0.84 POLB (0.37) TSHRPOLBCA12CA1CA2
SCHEMBL9424637 0.82 POLB (0.44) TSHRPOLBCA12HSD17B10ALDH1A1
SCHEMBL2240359 0.81 CYP3A4 (0.45) TSHRPOLBCA1CA2ALDH1A1
SCHEMBL22662253 0.79 TSHR (0.44) TSHRPPARDCA12CA1CA2
SCHEMBL8161275 0.79 TSHR (0.44) TSHRPPARDCA12CA1CA2
SCHEMBL15439350 0.79 TSHR (0.45) TSHRPPARDPOLBCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116987034-A 5- ((4-chloro-2, 3-dihydro-1H-inden-1-yl) methyl) -1H-imidazole and synthetic method thereof 安徽大学 2023-11-03 CN claimed
WO-2010084507-A2 PROCESS FOR THE PREPARATION OF N-METHYL-2-[3-(1-METHYL-4-PIPERIDYL)-1H-INDOL-5-YL]-ETHANESULFONAMIDE AND ITS ACID ADDITION SALTS SUN PHARMACEUTICAL INDUSTRIES LTD. (IN) 2010-07-29 WO claimed
US-20240128511-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY USING SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2024-04-18 US disclosed
US-11942601-B2 Nonaqueous electrolyte solution and nonaqueous electrolyte battery using same MITSUBISHI CHEMICAL CORPORATION (JP) 2024-03-26 US disclosed
CN-116987034-A 5- ((4-chloro-2, 3-dihydro-1H-inden-1-yl) methyl) -1H-imidazole and synthetic method thereof 安徽大学 2023-11-03 CN disclosed
WO-2023125373-A1 METHOD FOR PREPARING RUXOLITINIB AND INTERMEDIATE THEREOF 江苏威凯尔医药科技有限公司 2023-07-06 WO disclosed
US-20220336858-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY USING SAME MITUSBISHI CHEMICAL CORPORATION (JP) 2022-10-20 US disclosed
US-11424482-B2 Nonaqueous electrolyte solution and nonaqueous electrolyte battery using same MITSUBISHI CHEMICAL CORPORATION (JP) 2022-08-23 US disclosed
CN-105449189-B Lithium secondary battery 麦克赛尔控股株式会社 2020-12-01 CN disclosed
CN-105576279-B Lithium secondary battery 麦克赛尔控股株式会社 2020-05-12 CN disclosed
US-20190334208-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND NONAQUEOUS ELECTROLYTE BATTERY USING SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2019-10-31 US disclosed
EP-0711773-B1 HYMENIALDISINE AND DERIVATIVE THEREOF, PROCESS FOR PRODUCING INTERMEDIATE FOR SYNTHESIZING THE SAME, AND SAID INTERMEDIATE SUNTORY LTD (JP) 2001-09-12 EP disclosed
EP-0889877-B1 META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS SEARLE & CO (US) 2001-08-29 EP disclosed
EP-1029382-A1 COMPOSITE SUITABLE FOR USE IN ELECTROCHEMICAL CELLS BASF AKTIENGESELLSCHAFT (DE) 2000-08-23 EP disclosed
WO-1999019917-A2 COMPOSITE SUITABLE FOR USE IN ELECTROCHEMICAL CELLS BASF AKTIENGESELLSCHAFT (DE) 1999-04-22 WO disclosed
EP-0889877-A1 META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS G.D. SEARLE & CO. (US) 1999-01-13 EP disclosed
WO-1997036862-A1 META-SUBSTITUTED PHENYLENE DERIVATIVES AND THEIR USE AS ALPHAvBETA3 INTEGRIN ANTAGONISTS OR INHIBITORS G.D. SEARLE & CO. (US) 1997-10-09 WO disclosed
US-5621099-A CARDIOVASCULAR DISORDERS SUNTORY LIMITED (JP) 1997-04-15 US disclosed
EP-0711773-A1 HYMENIALDISINE AND DERIVATIVE THEREOF, PROCESS FOR PRODUCING INTERMEDIATE FOR SYNTHESIZING THE SAME, AND SAID INTERMEDIATE SUNTORY LIMITED (JP) 1996-05-15 EP disclosed
US-5025002-A Broad spectrum biocide, industrial process systems BROMINE COMPOUNDS LTD. (IL) 1991-06-18 US disclosed