SCHEMBL991

SCHEMBL991

COC(=O)CP(=O)(OC)OC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.46
POLB P06746 2/20 0.45
HSD17B10 Q99714 2/20 0.42
MGAM O43451 1/20 0.42
GAA P10253 1/20 0.42
SI P14410 1/20 0.42
MGAM2 Q2M2H8 1/20 0.42
CA12 O43570 2/20 0.38
CA14 Q9ULX7 2/20 0.38
KMT2A Q03164 2/20 0.34
TET2 Q6N021 1/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 3/20 0.33
KDM4E B2RXH2 1/20 0.33
RECQL P46063 1/20 0.33
ALDH1A1 P00352 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
HSP90AB1 P08238 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9424637 0.97 POLB (0.44) TSHRPOLBHSD17B10MGAMGAA
SCHEMBL29229754 0.91 POLB (0.40) TSHRPOLBHSD17B10MGAMGAA
SCHEMBL2236600 0.84 TSHR (0.44) TSHRPOLBHSD17B10MGAMGAA
SCHEMBL8563170 0.84 ALDH1A1 (0.36) TSHRPOLBHSD17B10MGAMGAA
SCHEMBL1692276 0.83 POLB (0.38) TSHRPOLBHSD17B10MGAMGAA
SCHEMBL28691228 0.81 TSHR (0.33) TSHRPOLBHSD17B10MGAMGAA
SCHEMBL2242177 0.81 POLB (0.37) TSHRPOLBHSD17B10MGAMGAA
SCHEMBL25295616 0.80 MGAM (0.33) TSHRPOLBMGAMGAASI
SCHEMBL6371680 0.80 POLB (0.42) TSHRPOLBHSD17B10MGAMGAA
SCHEMBL15438716 0.80 DGKA (0.35) TSHRPOLBLMNAALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3943 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059824-A Synthesis method of ilalastyl chiral intermediate 上海格苓凯生物科技有限公司 2026-05-19 CN claimed
EP-4677042-A1 LOW ELECTRICAL CONDUCTIVITY HEAT TRANSFER FLUID Prestone Products Corporation (US) 2026-01-14 EP claimed
US-20250206703-A1 PROCESS FOR PREPARING ((1S,2S)-2-(5-METHYLPYRIDIN-2-YL)CYCLOPROPYL)METHANOL MERCK SHARP & DOHME LLC (US) 2025-06-26 US claimed
CN-119798105-A Preparation method of milabalin 长治医学院 2025-04-11 CN claimed
CN-119768006-A Perovskite film and preparation method and application thereof 中国华能集团清洁能源技术研究院有限公司 2025-04-04 CN claimed
CN-119708053-A Phosphorylacetic acid method for synthesizing trimethyl ester 太仓运通新材料科技有限公司 2025-03-28 CN claimed
CN-119661529-A Synthesis method of 3, 9-diazaspiro [5.5] undecane-3-tert-butyl formate 上海馨远医药科技有限公司 2025-03-21 CN claimed
US-20250051513-A1 POLYESTER RESIN AND PREPARATION METHOD THEREFOR KOLON INDUSTRIES, INC. (KR) 2025-02-13 US claimed
EP-4504703-A1 PROCESS FOR PREPARING ((1S,2S)-2-(5-METHYLPYRIDIN-2-YL)CYCLOPROPYL)METHANOL Merck Sharp & Dohme LLC (US) 2025-02-12 EP claimed
CN-119100922-A Preparation method of bicyclo [3.1.1] heptane-3-ketone and intermediate thereof 南京富润凯德生物医药有限公司 2024-12-10 CN claimed
EP-1385814-A1 ENANTIOMERICALLY SELECTIVE CYCLOPROPANATION The University of Adelaide (AU) 2004-02-04 EP claimed
WO-2003027129-A1 BETA-KETOPHOSPHONATES RHODIA CONSUMER SPECIALTIES LIMITED (GB) 2003-04-03 WO claimed
US-6468939-B1 ESTERS OF PHOSPHORIC ACID, PHOSPHOROUS ACID, PHOSPHONIC ACID, PHOSPHONOUS ACID, PHOSPHINIC ACID OR PHOSPHINOUS ACID; COMPLEXING LIGANDS BAYER AKTIENGESELLSCHAFT (DE) 2002-10-22 US claimed
WO-2002079136-A1 ENANTIOMERICALLY SELECTIVE CYCLOPROPANATION THE UNIVERSITY OF ADELAIDE (AU) 2002-10-10 WO claimed
US-6376230-B1 Stereoselective process for producing intermediates of cryptophycins ELI LILLY AND COMPANY 2002-04-23 US claimed
US-5665802-A REACTING POLYAMIC ACID WITH A DEHYDRATION-CYCLIZATION AGENT, A CATALYST AND AN ORGANIC PHOSPHORUS COMPOUND; EXCELLENT IN TENSILE STRENGTH AND FLEXIBILITY KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1997-09-09 US claimed
EP-0205040-B1 METHOD FOR CLEANING A WORKPIECE AFTER MACHINING WITH A CUTTING INSTRUMENT International Business Machines Corporation (US) 1991-08-28 EP claimed
EP-0205040-A2 Method for cleaning a workpiece after machining with a cutting instrument International Business Machines Corporation (US) 1986-12-17 EP claimed
US-4599134-A Plasma etching with tracer IBM CORPORATION (US) 1986-07-08 US claimed
US-4520101-A FERMENTATION WITH ADDITION OF PHOSPHORUS COMPOUNDS BRISTOL-MYERS COMPANY (US) 1985-05-28 US claimed