Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 10/20 | 0.46 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | CPT2 | P23786 | 1/20 | 0.40 |
| ▸ | CPT1A | P50416 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22366353 | 0.83 | ABHD6 (0.48) | S1PR5ABHD6HRH3CPT2CPT1A | |
| SCHEMBL22319878 | 0.78 | ABHD6 (0.54) | S1PR5ABHD6HRH3CPT2CPT1A | |
| SCHEMBL22319858 | 0.77 | ABHD6 (0.55) | S1PR5ABHD6HRH3CPT2CPT1A | |
| SCHEMBL22319845 | 0.76 | ABHD6 (0.54) | S1PR5ABHD6HRH3CPT2CPT1A | |
| SCHEMBL20983789 | 0.76 | ABHD6 (0.69) | S1PR5ABHD6HRH3CPT2CPT1A | |
| SCHEMBL17607362 | 0.75 | ACACB (0.51) | ABHD6CPT2CPT1A | |
| SCHEMBL25384043 | 0.73 | ABHD6 (0.50) | S1PR5ABHD6HRH3CPT2CPT1A | |
| SCHEMBL28864977 | 0.72 | ABHD6 (0.49) | ABHD6CPT2CPT1AHPGDHSD17B10 | |
| SCHEMBL22319832 | 0.72 | ABHD6 (0.50) | S1PR5ABHD6HRH3CPT2CPT1A | |
| SCHEMBL5773186 | 0.72 | HRH3 (0.47) | S1PR5ABHD6HRH3CPT2CPT1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3700911-A1 | NOVEL MACROCYCLIC DERIVATIVES, PROCESS FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Les Laboratoires Servier SAS (FR) | 2020-09-02 | — | — | EP | disclosed |