Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.73 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAPDH | P04406 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31244838 | 1.00 | ALDH1A1 (0.73) | ALDH1A1POLBNPSR1CYP2C9RAB9A | |
| SCHEMBL6553986 | 1.00 | ALDH1A1 (0.73) | ALDH1A1POLBNPSR1CYP2C9RAB9A | |
| SCHEMBL6406054 | 0.97 | ALDH1A1 (0.69) | ALDH1A1POLBNPSR1CYP2C9RAB9A | |
| SCHEMBL9170845 | 0.89 | ALDH1A1 (0.61) | ALDH1A1POLBNPSR1CYP2C9RAB9A | |
| SCHEMBL10386833 | 0.89 | ALDH1A1 (0.61) | ALDH1A1POLBNPSR1CYP2C9RAB9A | |
| SCHEMBL21276016 | 0.87 | ALDH1A1 (0.63) | ALDH1A1POLBNPSR1CYP2C9RAB9A | |
| SCHEMBL11422899 | 0.87 | ALDH1A1 (0.63) | ALDH1A1POLBNPSR1CYP2C9RAB9A | |
| SCHEMBL10387571 | 0.86 | ALDH1A1 (0.58) | ALDH1A1POLBNPSR1CYP2C9RAB9A | |
| SCHEMBL9174125 | 0.86 | ALDH1A1 (0.58) | ALDH1A1POLBNPSR1CYP2C9RAB9A | |
| SCHEMBL9174080 | 0.86 | ALDH1A1 (0.58) | ALDH1A1POLBNPSR1CYP2C9RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092236-B1 | NOVEL GLUTAMINASE INHIBITORS | RHIZEN PHARMACEUTICALS S A (CH) | 2020-08-26 | — | — | EP | disclosed |